liver cancer Flashcards

1
Q

what are the types of liver cancer?

A

hepatocellular carcinoma 80%

cholangiocarcinoma 20%

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2
Q

what are the risk factors for hepatocellular carcinoma?

A

viral hepatitis (B and C)
alcohol
non alcoholic fatty liver disease
chronic liver disease

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3
Q

what disease is associated with cholangiocarcinoma?

A

Primary sclerosis cholangitis

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4
Q

signs of liver cancer?

A
late presentation = poor prognosis 
weight loss
abdominal pain
anorexia
nausea
vomiging 
jaundice
pruritus
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5
Q

sign of cholangiocarcinoma?

A

painless jaundice like pancreatic cancer

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6
Q

what is a tumour marker for hepatocellular carcinoma?

A

alpha fetoprotein

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7
Q

What is a tumour marker for cholangiocarcinoma?

A

CA19-9

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8
Q

investigations?

A

Liver ultrasound
CT
ERCP

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9
Q

treatment of hepatocellular carcinoma?

A

poor prognosis
resection
liver transplant
kinase inhibitors

CHEMO AND RADIOTHERAPY RESISTANT.

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10
Q

treatment of cholangiocarcinoma?

A

surgical resection

ERCP - stenting

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