liver cancer Flashcards
what are the types of liver cancer?
hepatocellular carcinoma 80%
cholangiocarcinoma 20%
what are the risk factors for hepatocellular carcinoma?
viral hepatitis (B and C)
alcohol
non alcoholic fatty liver disease
chronic liver disease
what disease is associated with cholangiocarcinoma?
Primary sclerosis cholangitis
signs of liver cancer?
late presentation = poor prognosis weight loss abdominal pain anorexia nausea vomiging jaundice pruritus
sign of cholangiocarcinoma?
painless jaundice like pancreatic cancer
what is a tumour marker for hepatocellular carcinoma?
alpha fetoprotein
What is a tumour marker for cholangiocarcinoma?
CA19-9
investigations?
Liver ultrasound
CT
ERCP
treatment of hepatocellular carcinoma?
poor prognosis
resection
liver transplant
kinase inhibitors
CHEMO AND RADIOTHERAPY RESISTANT.
treatment of cholangiocarcinoma?
surgical resection
ERCP - stenting