liver and gluconeogen Flashcards
1
Q
2 main ways gluconeogenesis is regulated
A
- mobilisation of substrate
2. activation of enzymes
2
Q
what are the enzymes involved in gluconeogen regulation
A
G6Pase F1
6bisPase
PEPCK
act of pyruvate carboxylase by acetyl CoA
3
Q
what substrates are mobilised in gluconeo regulation
A
- glycerol - fat breakdown
- amino acids - muscle protein breakdown
4
Q
what 3 enzymes catalyse reactions in the cytosol that must be bypassed for gluconeo
A
glucokinase/hexokinase
phosphofructokinase
pyruvate kinase PEP –> pyruvate
