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FBS 1 metabolism > anaerobic metabolism > Flashcards

anaerobic metabolism Flashcards

1
Q

what are the 4 stages of glycolysis

A

activation (use ATP)
split 6C sugar in half
oxidise (remove 2H)
synthesise ATP

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2
Q

products and reactants of the 3 steps of activation

A

D glucose
–> glucose-6-phosphate [uses ATP] [hexokinase or glucokinase]
fructose-6-phosphate [phosphoglucose isomerase]
–> fructise-6-biphosphate [uses ATP] [phosphofructo-kinase]

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3
Q

enzymes used in the activation stages

A

hexokinase or glucokinase
phosphoglucose isomerase
phosphofructo-kinase

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4
Q

equations for the splitting stage in glycolysis

A

fuctose-6-biphosphate [splits]
–> dihydroxyacetone phosphate and glyceraldehyde 3-phosphate

both these products react

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5
Q

enzymes for splitting stage

A

aldose A

triose phosphate isomerase for the reactions between the products of splitting

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6
Q

oxidation stage of glycolysis

A

glyceraldegyde-6-phosphate 1,3-biphosphoglycerate

[uses Pi, interconvers betwee NAD+ NADH + H+]

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7
Q

enzyme used in oxidation - glycolysis

A

glyceraldehyde 3-phosphate dehydrogenase

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8
Q

reaction 1 glycololysis

A

D glucose –> glucose-6-phosphate [uses ATP]

hexokinase or glucokinase

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9
Q

reaction 2 of glycolysis

A

glucose-6-phosphate fructose-6-phosphate

phosphoglucose isomerase

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10
Q

reaction 3 of glycolysis

A

fructose-6-phosphate –> fructise-6-biphosphate [uses ATP]

phosphofructo-kinase

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11
Q

what does NAD stand for

A

nicotinamine adenine dinucleotide

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12
Q

ATP synthesis - 1/4 reaction

A

1,3-biphosphoglycerate 3-phosphoglycerate

phosphoglycerate kinase

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13
Q

ATP synthesis - 2/4

A

3-phosphoglycerate 2-phosphoglycerate

phosphoglycerate mutase

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14
Q

ATP synthesis 3/4

A

2-phosphoglycerate phosphoenol pyruvate [+ H20]

Enolase

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15
Q

ATP synthesis 4/4

A

phosphoenol pyruvate –> pyruate +ATP

pyruvate kinase

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16
Q

net ATP production for glycolysis

A

2

17
Q

anaerobic glycolysis in the different tissues

A

pyrivate +NADH + H –> L-lactate + NAD+
in muslce
(opposite in muscle)
lactate dehydrogenase

FBS 1 metabolism (10 decks)

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