Liver and Gall Bladder Flashcards

1
Q

What are the 4 lobes of the liver?

A

right, left, quadrate, caudate

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2
Q

Ligaments of the liver

A

falciform ligament: sheet of mesentery that suspends the liver from the diaphragm and anterior abdominal wall

round ligament: carries blood from the umbilical cord to the liver of a fetus

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3
Q

Vessels attached to the liver

A
  • hepatic portal vein
  • hepatic arteries
  • hepatic veins
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4
Q

Types of liver cells

A
  • hepatocyte
  • stellate macrophages
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5
Q

Function of hepatocytes

A
  • absorbs glucose, amino acids, iron, vitamins, and other nutrients for metabolism or storage
  • remove and degrade hormones, toxins, bile pigments, and drugs
  • secretes albumin, lipoproteins, clotting factors, angiotensinogen
  • breakdown stored glycogen and release glucose into the circulation
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6
Q

Function of stellate macrophages

A

remove bacteria and particulate debris from the blood

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7
Q

How does blood flow to the liver?

A

hepatic portal vein: brings blood from the stomach, intestines, pancreas, and spleen

hepatic arteries: delivers oxygen to the liver

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8
Q

How does blood flow from the liver?

A
  • central vein
  • hepatic veins
  • empties into the inferior vena cava
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9
Q

Which vessels are oxygen-rich?

A

hepatic arteries

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10
Q

Which vessels are oxygen-poor?

A

hepatic portal vein

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11
Q

Which vessels are nutrient rich?

A

hepatic portal vein

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12
Q

What is a lobule?

A

structural unit of the liver

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13
Q

How many lobules are in each lobe?

A

100,000

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14
Q

What are the components of each lobule?

A

hexagonal collections of hepatocytes partitioned by connective tissue

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15
Q

How does blood flow through the lobules?

A
  • blood enters the liver sinusoids via the hepatic portal vein and hepatic arteries
  • blood collects in the central vein at the core of the lobule after being processed by the hepatocytes
  • blood collects in the central vein then empties into the inferior vena cava via the hepatic veins
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16
Q

What is bile?

A

watery solution of minerals, cholesterol, neutral fats, phospholipids, bile pigments, bile acids, and lipid-transport vesicles

17
Q

Where is bile made?

18
Q

What are bile salts?

A

steroids synthesized from cholesterol

19
Q

What do bile salts do?

A

aids in fat digestion and absorption

20
Q

What is the route bile takes?

A
  • bile is secreted by hepatocytes into the bile canaliculi
  • bile flows into the bile ductules
  • bile ductules converge to form left and right hepatic ducts
  • left and right hepatic ducts form the common hepatic duct
  • common hepatic duct joins the cystic duct to form the bile duct
  • bile duct joints with the pancreatic duct to form the hepatopancreatic ampulla
  • hepatopancreatic ampulla empties into the duodenum
21
Q

General functions of the liver

A
  • bile production
  • storage and release of glycogen, lipids, vitamins, and minerals
  • conversion of nutrients
  • detoxification
  • synthesis of plasma proteins
  • phagocytosis
22
Q

Functions of the gallbladder

A

receives, stores, and concentrates bile produced by the liver

23
Q

What causes the release of bile into the intestines?

A

cholecystokinin (CCK) triggers contractions of the gallbladder and relaxation of the hepatosphincter, discharging bile into the duodenum

24
Q

What does the bile travel through to get from the gallbladder to the duodenum?

A
  • gallbladder
  • cystic duct
  • bile duct
  • hepatopancreatic duct
  • major duodenal papilla
  • duodenum
25
What are gallstones?
hard masses in the gallbladder or bile ducts composed of cholesterol, calcium carbonate, and bilirubin