Liver Flashcards

1
Q

Synonym for viral Hep A

A

HAV

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2
Q

Hepatitis C synonym:

A

HCV

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3
Q

Hepatitis C Pathophys:

A

RNA virus provokes a cell-mediated response that causes liver injury.

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4
Q

Hepatitis virus incubates for how long?

A

2 months

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5
Q

How is Hepatitis C transmitted?

A
  • Transmitted though percutaneous injection by IV drug users

- Exposure to blood products

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6
Q

Hepatitis C risk factor:

A

Exposure to blood products

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7
Q

Hepatitis C signs and symptoms:

A

Moderate in presentation and progresses to chronic hepatitis

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8
Q

Hepatitis C prevention:

A

No known prevention, best to avoid exposure

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9
Q

Hepatitis C treatment:

A
  • Therapy with interferon and lamivudine

- Vaccine considered impractical

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10
Q

Vaccine for treatment of __________ is considered impractical.

A

Hepatitis C

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11
Q

HDV synonym:

A

Hepatitis D

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12
Q

Which hepatitis has 1-3 month incubation period?

A

Hepatitis D

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13
Q

Hepatitis D pathophys:

A
  • 1-3 month incubation period, which causes acute or insidious-onset liver disease
  • Often superimposed over HBV infection - contributes to chronic hepatitis
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14
Q

Pathophysio: RNA virus incubates for 1 month and replicates in liver

A

HAV. Viral HEP A

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15
Q

Pathophysio: Causes IgM response that converts to IgG response after 5 months

A

Viral Hep A/ HAV

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16
Q

Pathophysio: Virus incubates for 2-3 months. Small DNA virus replicates in the liver but can live elsewhere in spleen, lymph nodes and pancreas

A

Hep B/ HBV

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17
Q

Associated with liver carcinoma

A

Hep B/ HBV

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18
Q

Transmission: fecal-oral route is primary form of transmission

A

HAV/ Viral Hep A

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19
Q

Transmission: linked to poor hygiene with food prep, areas of overcrowding, contaminated shellfish

A

Viral Hep A/ HAV

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20
Q

May cause jaundice/ mild presentation

A

Viral hep A/ HAV

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21
Q

NO liver destruction, great prognosis

A

Viral Hep A/HAV

22
Q

Hepatitis E treatment:

A
  • It has good prognosis with no treatment

- No prophylaxis or therapy is done

23
Q

Mostly in babies, children, toddlers and young adults

A

Hep B/ HBV

24
Q

High risk in hospital workers, spouse of infected, prisoners

A

Hep B/ HBV

25
Detection: Diagnosed by detection of IgM/ long term IgG
V Hep A
26
Insidious or acute onset
Hep B
27
Can lead to liver cancer
Hep B
28
Hepatic Necrosis (rare)
Hep B
29
Limited therapy (not necessary) used to treat
V. Hep A
30
Improved sanitation to reduce incidence
V Hep A
31
Immunization recommended to daycare workers, tourists in poor sanitation, family members infected, Alaskans
V Hep A
32
DETECTION: serological and virologic markers
Hep B
33
Vaccine recommended for prisoners, hemophiliacs, health care workers, IV drug users, children under 18 and sexually active
Hep B
34
Pathophysio: upper right part of liver
Alcoholic Liver Disease and Cirrhosis
35
Pathophysio: excessive consumption of alcohol
Cirrhosis
36
3 beers a day for 10 years leads to
fatty liver - liver enlargement
37
5 beers a day for 10 years leads to
severe liver disease
38
7 beers a day for 10 years leads to
cirrhosis
39
Chronic injury to the liver, fibrosis of the liver, liver cell necrosis and scarring, distorted vascular supply
Cirrhosis
40
Pathophysio: inhibition of bile flow resulting in jaundice
Gallstone obstruction
41
Concretion of bile that consists of cholesterol, calcium bilirubinate and other salt, protein and fatty acids
Gallstone
42
Obstruction of the cystic duct
Gallstone obstruction
43
Upper right quadrant pain
Gallstone obstruction
44
Hepatitis D risk factors:
Prominent among intravenous drug abusers and certain ethnic populations
45
Hepatitis D is transmitted:
- Spread by close personal contact | - Exposure to blood-borne products
46
Hepatitis D Treatment:
No treatment
47
HDV can be prevented by:
HBV vaccine Therapy with the use of interferon
48
Hepatitis E aka:
HEV
49
HEV pathophys:
- RNA virus with 2 week to 2 month incubation period - Causes an acute liver disease in young adults - Does NOT progress into chronic liver disease
50
Hepatitis ____ does not progress into a chronic disease.
E
51
HEV transmission:
- Fecal-oral transmission - Occurs after major floods due to water contamination - Transmission is rarely person to person
52
Hepatitis E is more prevalent among ______.
Young adults