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Clinical Medicine > Liver > Flashcards

Liver Flashcards

1
Q

Synonym for viral Hep A

A

HAV

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2
Q

Hepatitis C synonym:

A

HCV

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3
Q

Hepatitis C Pathophys:

A

RNA virus provokes a cell-mediated response that causes liver injury.

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4
Q

Hepatitis virus incubates for how long?

A

2 months

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5
Q

How is Hepatitis C transmitted?

A
  • Transmitted though percutaneous injection by IV drug users

- Exposure to blood products

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6
Q

Hepatitis C risk factor:

A

Exposure to blood products

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7
Q

Hepatitis C signs and symptoms:

A

Moderate in presentation and progresses to chronic hepatitis

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8
Q

Hepatitis C prevention:

A

No known prevention, best to avoid exposure

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9
Q

Hepatitis C treatment:

A
  • Therapy with interferon and lamivudine

- Vaccine considered impractical

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10
Q

Vaccine for treatment of __________ is considered impractical.

A

Hepatitis C

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11
Q

HDV synonym:

A

Hepatitis D

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12
Q

Which hepatitis has 1-3 month incubation period?

A

Hepatitis D

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13
Q

Hepatitis D pathophys:

A
  • 1-3 month incubation period, which causes acute or insidious-onset liver disease
  • Often superimposed over HBV infection - contributes to chronic hepatitis
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14
Q

Pathophysio: RNA virus incubates for 1 month and replicates in liver

A

HAV. Viral HEP A

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15
Q

Pathophysio: Causes IgM response that converts to IgG response after 5 months

A

Viral Hep A/ HAV

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16
Q

Pathophysio: Virus incubates for 2-3 months. Small DNA virus replicates in the liver but can live elsewhere in spleen, lymph nodes and pancreas

A

Hep B/ HBV

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17
Q

Associated with liver carcinoma

A

Hep B/ HBV

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18
Q

Transmission: fecal-oral route is primary form of transmission

A

HAV/ Viral Hep A

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19
Q

Transmission: linked to poor hygiene with food prep, areas of overcrowding, contaminated shellfish

A

Viral Hep A/ HAV

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20
Q

May cause jaundice/ mild presentation

A

Viral hep A/ HAV

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21
Q

NO liver destruction, great prognosis

A

Viral Hep A/HAV

22
Q

Hepatitis E treatment:

A
  • It has good prognosis with no treatment

- No prophylaxis or therapy is done

23
Q

Mostly in babies, children, toddlers and young adults

A

Hep B/ HBV

24
Q

High risk in hospital workers, spouse of infected, prisoners

A

Hep B/ HBV

25
Q

Detection: Diagnosed by detection of IgM/ long term IgG

A

V Hep A

26
Q

Insidious or acute onset

A

Hep B

27
Q

Can lead to liver cancer

A

Hep B

28
Q

Hepatic Necrosis (rare)

A

Hep B

29
Q

Limited therapy (not necessary) used to treat

A

V. Hep A

30
Q

Improved sanitation to reduce incidence

A

V Hep A

31
Q

Immunization recommended to daycare workers, tourists in poor sanitation, family members infected, Alaskans

A

V Hep A

32
Q

DETECTION: serological and virologic markers

A

Hep B

33
Q

Vaccine recommended for prisoners, hemophiliacs, health care workers, IV drug users, children under 18 and sexually active

A

Hep B

34
Q

Pathophysio: upper right part of liver

A

Alcoholic Liver Disease and Cirrhosis

35
Q

Pathophysio: excessive consumption of alcohol

A

Cirrhosis

36
Q

3 beers a day for 10 years leads to

A

fatty liver - liver enlargement

37
Q

5 beers a day for 10 years leads to

A

severe liver disease

38
Q

7 beers a day for 10 years leads to

A

cirrhosis

39
Q

Chronic injury to the liver, fibrosis of the liver, liver cell necrosis and scarring, distorted vascular supply

A

Cirrhosis

40
Q

Pathophysio: inhibition of bile flow resulting in jaundice

A

Gallstone obstruction

41
Q

Concretion of bile that consists of cholesterol, calcium bilirubinate and other salt, protein and fatty acids

A

Gallstone

42
Q

Obstruction of the cystic duct

A

Gallstone obstruction

43
Q

Upper right quadrant pain

A

Gallstone obstruction

44
Q

Hepatitis D risk factors:

A

Prominent among intravenous drug abusers and certain ethnic populations

45
Q

Hepatitis D is transmitted:

A
  • Spread by close personal contact

- Exposure to blood-borne products

46
Q

Hepatitis D Treatment:

A

No treatment

47
Q

HDV can be prevented by:

A

HBV vaccine

Therapy with the use of interferon

48
Q

Hepatitis E aka:

A

HEV

49
Q

HEV pathophys:

A
  • RNA virus with 2 week to 2 month incubation period
  • Causes an acute liver disease in young adults
  • Does NOT progress into chronic liver disease
50
Q

Hepatitis ____ does not progress into a chronic disease.

A

E

51
Q

HEV transmission:

A
  • Fecal-oral transmission
  • Occurs after major floods due to water contamination
  • Transmission is rarely person to person
52
Q

Hepatitis E is more prevalent among ______.

A

Young adults

Clinical Medicine (7 decks)

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