Endocrine Quiz Flashcards

1
Q

Type I DM formerly known as:

A

Insulin dependent DM

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2
Q

Complete loss of insulin-producing beta cells in the pancreas results in type ___ DM.

A

I

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3
Q

Hyper/hypoglycemia is assiciated with DM I.

A

Hyperglycemia

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4
Q

High serum glucose level causes ____ cells to be destroyed.

A

Ilet

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5
Q

Glucose cannot be taken into the body as it should in this Dz.

A

DM I

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6
Q

Identify the Dz.

Risk: lean, 30 yo, requires insulin, develops ketoacidosis and autoimmune Dz.

A

DM I

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7
Q

Excessive hunger (polyphasia) and thirst (polydipsia) are common symptoms of:

A

DM I

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8
Q

C-peptide test is done to detect what Dz and why?

A

DM I; Tests to tell how much pancreas function remains.

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9
Q

Fasting plasma glucose level of 126 mg/dl pr above is a sign of:

A

DM I

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10
Q

1A-autoimmune destruction on beta cells is a subtype of:

A

DM I

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11
Q

1B-idiopathic destruction on the beta cells is a subtype of:

A

DM I

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12
Q

What is the pathophysiologic sugar level in DM I?

A

Sustained elevated blood sugar > 126 mg

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13
Q

In DM I excessive thirst is caused by:

A

water shifting out of cells and into the blood.

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14
Q

Define Polyuria.

A

Production of abnormally large volume of dilute urine, which is an effect of glucose in the blood after kidney filtration.

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15
Q

HbA1c blood test is for long term glycemic control of which Dz?

A

DM I

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16
Q

What is a common treatment for DM I?

A

Insulin injections.

No oral diabetic medications.

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17
Q

Tier 1 or 2? Hyperthyroidism

A

T1

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18
Q

Risk factors of DM II:

A
  • Obesity
  • Genetic predisposition
  • > 45 yo
  • African American
  • Native American
  • Stimulated by other drugs and environmental factors
  • Infections of pancreas and endocrine system
  • Elevated cholesterol and BP
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19
Q

These are the signs and symptoms of what Dz?

  • Shortness of breath
  • Nausea
  • Vomiting
  • Altered mental fxn
  • Possible syndrome X
A

DM II

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20
Q

Risk factors for this disease include age (25-50), and 10 times more common in women than men

A

Hyperthyroidism

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21
Q

Signs, Symptoms and effects:

Prominent stare
Excessive nervousness
Insomnia
Hyperactivity
Palpitations
A

Hyperthyroidism

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22
Q

Hyperthyroidism is associated with weight ____ and _____ appetite

A

weight loss, appetite

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23
Q

Signs, Symptoms and effects:

Digit tremors, fatigue, heat intolerance, weakness

A

Hyperthyroidism

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24
Q

Goiter is a sign of what disease?

A

Hyperthyroidism

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25
Detected by elevated T4 levels
Hyperthyroidism
26
Treated with drugs, radioiodine therapy for patients over the age of 40, and sometimes surgery
Hyperthyroidism
27
Basic pathophysiology of ___? Insufficient amount of thyroid hormone, and reduces metabolic state.
Hypothyroidism
28
This disease is most commonly a cause of Hashimotos. Name the subtype
Hypothyroidism (secondary)
29
Secondary hypothyroidism happens in the
pathway
30
Primary hypothyroidism is caused by _______ often by ______
damage to the thyroid, tx of hyperthyroidism
31
Signs, Symptoms and effects: Cold intolerance Peripheral Paresthesia Bloating
Hypothyroidism
32
Detection: lab test for elevated TSH of low free T4
Hypothyroidism
33
Treated with levothyroxine
Hypothyroidism
34
Basic pathophysiology of ____? Benign tumor in pituitary Most common cause of pituitary dysfunction in adults
Pituitary Adenoma
35
Signs, symptoms & effects: Hair & Skin texture difference Sexual dysfunction Gigantism in children
Pituitary Adenoma
36
Can lead to nerve palsy, headaches, visual disturbance
Pituitary Adenoma
37
Can cause Cushing's Disease if produces ACTH (Acetylcholine)
Pituitary Adenoma
38
Surgical removal of tumor, or radiation
Pituitary Adenoma
39
Increase in glucose production by the liver, insulin resistance and decreased insulin production. Name the Dz:
DM II
40
Risk factors of DM II:
- Obesity - Genetic predisposition - >45 yo - African American - Native American - Stimulated by other drugs and environmental factors - Infections of pancreas and endocrine system - Elevated cholesterol and BP
41
These are the signs and symptoms of what Dz? - Shortness of breath - Nausea - Vomiting - Altered mental fxn - Possible syndrome X
DM II
42
Treatments for DM II:
- Oral glucose lowering agents - No insulin injection required - Exercise reduction of glucose intolerance
43
Name the tier 1 Dz of the endocrine system.
- DM I - DM II - Hyperthyroidism - Hypothyroidism - Pituitary Adenoma
44
Menopause is a tier 1 or 2 "Dz" of the endocrine system.
Tier 2
45
Progressive loss of ovarian fxn culminating in the final episode of menstrual bleeding. Name the "Dz."
Menopause
46
What hormone levels are reduced in menopause?
Estrogen and androgen
47
What are the symptoms of menopause?
Hot flashes, skin atrophy, decreased breast size, osteoporosis.
48
Tier 1 or 2? Hypothyroidism
T1
49
Tier 1 or 2? Pituitary Adenoma
T1
50
Pathophysiology: Caused by prolonged use of glucocoticoids, or hyperactive adrenal gland
Cushing's syndrome
51
Causes elevated cortisol levels
Cushing's Syndrome
52
Rare disorder caused by the destruction of adrenal glands (autoimmune usually)
Addison's Disease
53
Can be caused by TB and histoplasmic granulomatous infiltration
Addison's Disease
54
Deficiency in cortisol
Addison's Disease
55
Small benign tumor most often found in the adrenal medulla (can also develop around the sympathetic ganglia?
Pheochromocytoma
56
Secretes excessive catecholamines
Pheochromocytoma
57
Significant cause of secondary systemic hypertension
Pheochromocytoma
58
Inflammation of the thyroid gland results in:
Hashimotos Thyroiditis
59
The most common thyroid Dz, most common cause of goiter, and most common autoimmune Dz:
Hashimotos Thyroiditis
60
Vascular damage to pituitary gland resulting from an acute hemorrhage in the gland mostly caused by trauma
Pituitary Apoplexy
61
Causes severe hypoglycemia and drop in blood pressure
Pituitary Apoplexy
62
Tier 1 or 2? Hashimotos Thyroiditis
T2
63
Tier 1 or 2? Pituitary Apoplexy
T2
64
Tier 1 or 2? Cushing's Syndrome
T2
65
Tier 1 or 2? Addison's Disease
T2
66
Tier 1 or 2? Pheochromocytoma
T2