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Gastroenterology > Liver > Flashcards

Liver Flashcards

1
Q

What are the anti-ox that can be used for liver protection?

A

n-acetylcysteine and silymarin

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2
Q

Common causes in dog vs cat of extrahepatic BD obstruction

A
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3
Q

breeds associated with chronic hepatitis

A

doby and spaniels

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4
Q

Breeds and related genetic defects for copper associated chronic hepatitis

A
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5
Q

What is the biochem makeup of chronic hepatitis

A
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6
Q

How can chronic hepatitis differ from reactive hepatopathy?

A

RH- no necresis, inflammation

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7
Q

normal copper tissue level?

stain for copper?

distribution?

A

<400 ug/g

rhodanine stain

centrilobular

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8
Q

Tx for chronic hepatitis

A
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9
Q

Chelators for copper chronic hep?

A

D-penicillamine

trientine

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10
Q

C.S. cirrhosis

A
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11
Q

How does the body deal with hypertension from cirrhosis?

A

secondary shunts

activate RAAS system (absorb more Na/H2O from kidneys)

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12
Q

Tx for cirrhosis

A

spironolactone

anti-fibrotics

(not furosemide- hypoK & metabolic alkalosis-worsen hepatic encephalopathy)

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13
Q

Anti-fibrotic

A

pred or colchicine

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14
Q

Tx for hepatic encephalopathy

A

lactulose (increase motility GI and change pH to make absorption ammonia harder)

abx- neomycin & amoxi

restirct protein diet

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15
Q

pre-disposed breeds for congenital PSS

A
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16
Q

urate stones are often associated with what condition?

Which breeds is it normal?

A

PSS

dalmation and bulldog

17
Q

Two classic signs of PSS in cats

A

ptyalism and copper irises

stunted growth

18
Q

Common biochem findings for congenital PSS

A

ammonium biurate crystals

microcytic anemia

19
Q

Tx for congenital PSS

A
20
Q

Key biochem findings with vacuolar hepatopathy

A

high ALP but normal BR

21
Q

Tx for vacuolar hepatopathy

A
22
Q

the most common cause of incrase liver enzymes is

A

extra-hepatic dz

23
Q

Key findings with reactive hepatopathies?

A

no necrosis

neutrophilic vs. mononuclear inflammation

24
Q

hepatitis in the dog is to ….. in the cat

A

cholangitis

25
Q

Namt the two types of cholangitis

A
26
Q

breed for lymphocytic cholangitis in cats

A

persians

27
Q

type of anemia associated with cholangitis

A

non-regen normochromic, normocytic

28
Q

Tx for NT cholangitis

A
29
Q

Tx for lymphocytic cholangitis

A
30
Q

Risk factor for hepatic lipidosis

A

rapid weight loss and obesity

31
Q

biochem profile for hepatic lipidosis

A

increase ALP (more than ALT)

normal/midly increase GGT

32
Q

Tx for feline hepatic lipidosis

A

Gastroenterology (11 decks)

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