Liver Flashcards
1
Q
Child-Pugh Scoring System for Cirrhosis
A
1 pt, 2pt, 3pt with increasing severity Encephalopathy: none, grade 1-2, grade 3-4 Ascites: absent, slight, moderate/large Bilirubin (umol/L): 50 Albumin (g/L): 35 INR: 2.3
Child Class A = 5-6 pts
Child Class B = 7-9 pts
Child Class C = 10-15 pts
1 yr survival rates:
Class A = 100%
Class B = 80%
Class C = 50%
2
Q
Complications of Chronic Liver Disease
A
Portal hypertension ascites hypersplenism +/- spenomegaly lower oesophageal varices and rectal varices Synthetic dysfunction hypoalbuminaemia coagulopathy Hepatopulmonary syndrome Hepatorenal syndrome Encephalopathy Hepatocellular carcinoma
3
Q
Signs associated with Chronic Liver Disease
A
clubbing, palmar erythema, spider naevi
gynaecomastia, testicular atrophy, feminising hair distrib
small irregular shrunken liver, anaemia, caput medusa
4
Q
Signs associated with decompensation
A
Encephalopathy drowsiness asterixis hyperventilation Excretory dysfunction jaundice Hypoalbuminaemia ascities pulmonary oedema leukochonychia Portal HTN ascities Coagulopathy bruising Acid-base imbalance usually respiratory alkalosis
5
Q
Signs associated with aetiology
A
Alcohol dupuytren's contracture parotid enlargement peripheral neuropathy (+ some drugs) cerebellar signs hepatomegaly (+ NAFLD) Wilson's disease cerebellar signs Kayser-Fleisher rings Haemachromatosis increased skin pigmentation hepatomegaly Signs of right heart failure