Liver Flashcards

1
Q

Child-Pugh Scoring System for Cirrhosis

A
1 pt, 2pt, 3pt with increasing severity
Encephalopathy: none, grade 1-2, grade 3-4
Ascites:  absent, slight, moderate/large
Bilirubin (umol/L): 50
Albumin (g/L): 35
INR:  2.3

Child Class A = 5-6 pts
Child Class B = 7-9 pts
Child Class C = 10-15 pts

1 yr survival rates:
Class A = 100%
Class B = 80%
Class C = 50%

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2
Q

Complications of Chronic Liver Disease

A
Portal hypertension 
    ascites
    hypersplenism +/- spenomegaly
    lower oesophageal varices and rectal varices
Synthetic dysfunction
    hypoalbuminaemia
    coagulopathy
Hepatopulmonary syndrome
Hepatorenal syndrome
Encephalopathy
Hepatocellular carcinoma
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3
Q

Signs associated with Chronic Liver Disease

A

clubbing, palmar erythema, spider naevi
gynaecomastia, testicular atrophy, feminising hair distrib
small irregular shrunken liver, anaemia, caput medusa

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4
Q

Signs associated with decompensation

A
Encephalopathy
   drowsiness
   asterixis
   hyperventilation
Excretory dysfunction
   jaundice
Hypoalbuminaemia
   ascities
   pulmonary oedema
   leukochonychia
Portal HTN
   ascities
Coagulopathy
   bruising
Acid-base imbalance
   usually respiratory alkalosis
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5
Q

Signs associated with aetiology

A
Alcohol
   dupuytren's contracture
   parotid enlargement
   peripheral neuropathy (+ some drugs)
   cerebellar signs
   hepatomegaly (+ NAFLD)
Wilson's disease
   cerebellar signs
   Kayser-Fleisher rings
Haemachromatosis
   increased skin pigmentation
   hepatomegaly
Signs of right heart failure
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