Listeria Flashcards
Listeria - Descriptive statement
Gram positive, motile peritrichous flagella, coccoid rod shaped, non acid fast catalase +, oxidase -, non-spore forming, Facultative anaerobe
Listeria CAMP positive with which species?
L. monocytogenes with Staph aureus - L. invanovii with R. equi
Listeria intracellular/extracellular?
Facultative intracellular in macrophages
Listeria Pathogenesis
Intestinal & CNS routes (via neural sheath of trigeminal nerve)
Listeria Virulence factors
ActA (hijack actin cytoskeleton for intracellular movement) - Internalins (adhesion & entry into cell) Listeriolysin O (main facor, pore-forming)
Listeria are associated with what type of food in domestic animals? What seasons most common
Silage - Silage diseases is classic. Winter & spring most
Listeria in ruminants
“M-A-C-E” - Mastitis - Abortion - Conjunctivitis- Encephalitis (Circling Diseases, perivascular cuffing seen on histo)
When I tell you a cow is circling, you might say
Listeria! -Likely death in 2-3 days
If perivascular cuffing is seen in ruminant CNS histology, you might think…
Listeria!
If a fetus is aborted late-term and appears macerated, or delivered weak and moribund, you think…
Listeria!
What type of bacteria is risky in unpasteurized milk, due to it’s subclinical infection of cows?
Listeria!
Listeria in birds
Myocardial necrosis - degenerative & serofibrinous pericarditis
Myocardial necrosis, degenerative & serofibrinous pericarditis in birds
Listeria!
Listeria in horses
Septicemia in neonates
Listeria in chinchillas
Particularly susceptible
