Erysipelothrix Flashcards
Erysipelothrix - Describing statement
Gram +, Coagulase +, Catalase/Oxidase Negative, Non-spore forming, , slender rods, H2S producers in TSI slant . Resistant to high salt concentrations & wide temp range
Erysipelothrix - virulence factors
Capsule & Neuraminidase (sialic acid cleavage–>thrombus–>adhesion)
Erysipelothrix- Pathogenesis
Attachment–> vascular damage & hyaline thrombus formation–> resistant to phagocytosis & survive inside if are engulfed (capsule)
Erysipelothrix in swine
“Diamond Skin Disease!” Pigs < 3 years are least susceptible (mom’s and own natural defenses) - Septic/acute form - Chronic form
When I say Diamond Skin disease or rhomboid patches on skin, you say…
Erysipelas in swine - E. rhusiopathiae
Septic form of Erysipelas in swine
Acute, high mortality rates if untreated
Chronic form of Erysipelas in swine
Significant Industry impact - Vegetative endocarditis - Arthritis, stiff gait - Abortion (heart, joints, abort!)
When I say vegetative endocarditis & arthritis & abortion in swine, you say…
Erysepelothrix rhysiopathiae - Chronic form
Erysipelas in birds
Especially Turkeys - Septicemia - Cyanotic! (blue) - Swollen snood (characteristic) - Chronic (vegetative endocarditis & arthritis)
If I say swollen snood on turkey, you say…
Erisepelas!
If I say vegetative endocarditis & arthritis on a turkey, you say…
Erisepelas!
Case study: Heifer with vegetative endocarditis
Erisepelas in a heifer!
Erysipelas in sheep
Polyarthritis
Erysipelas in dog
Endocarditis & arthritis
Erysipelas in dolphins
Septicemia & urticaria
Erysipelas in humans
Skin & subQ infection, common in animal & fish handlers
Describe the appearance of colonies on blood agar at 24 and 48hrs in Erysipelothrix rhusiopathiae
24 h: pin point colonies, no hemolysis
- 48hr: green zone of incomplete/alpha hemolysis
What happens in a TSI agar slant test with Erysipelothrix rhusiopathiae
H2S production !
Case Study- Vegetative endocarditis in heifer, in right AV valve. Suspect multiple septic thrombi caused infarction in the brain leading to ataxia & altered behavior
Erysipelothrix in a heifer