Lipids, Water, Inorganic ions - Biological Molecules Flashcards

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1
Q

Describe how to test for lipids in a sample.

A
  1. Dissolve solid samples in ethanol.
  2. Add an equal volume of water and
    shake.
  3. Positive result: milky white emulsion
    forms
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2
Q

Contrast saturated and unsaturated fatty acids.

A

Saturated:
● Contain only single bonds
● Straight-chain molecules
have many contact points
● Higher melting point = solid
at room temperature
● Found in animal fats

Unsaturated:
● Contain C=C double bonds
● ‘Kinked’ molecules have
fewer contact points
● Lower melting point = liquid
at room temperature
● Found in plant oils

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3
Q

How do triglycerides form?

A

condensation reaction between 1 molecule of glycerol & 3 fatty acids forms ester bonds

check google for picture explanation

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4
Q

Describe the structure and function of phospholipids.

A

Amphipathic molecule: glycerol backbone attached to 2 hydrophobic fatty acid tails & 1 hydrophilic polar phosphate head.
● Forms phospholipid bilayer in water = component of membranes.
● Tails can splay outwards = waterproofing.

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5
Q

Relate the structure of triglycerides to their functions.

A

● High energy:mass ratio = high calorific value from oxidation (energy storage).
● Insoluble hydrocarbon chain = no effect on water potential of cells & used for waterproofing.
● Slow conductor of heat = thermal insulation e.g. adipose tissue.
● Less dense than water = buoyancy of aquatic animals.

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6
Q

Contrast phospholipids and triglycerides.

A

phospholipids:
● 2 fatty acids & 1 phosphate group attached
● Hydrophilic head & hydrophobic tail
● Used primarily in membrane formation

triglycerides:
● 3 fatty acids attached
● Entire molecule is
hydrophobic
● Used primarily as a
storage molecule (oxidation releases energy)

They are attached to glycerol

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7
Q

Compare phospholipids and triglycerides.

A

● Both have glycerol backbone.
● Both may be attached to a mixture of
saturated, monounsaturated &
polyunsaturated fatty acids.
● Both contain the elements C, H, O.
● Both formed by condensation reactions.

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8
Q

Are phospholipids and triglycerides polymers?

A

No; they are not made from a small repeating unit. They are macromolecules.

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9
Q

Why is water a polar molecule?

A

O is more electronegative than H, so attracts the electron density in the covalent bond more strongly.
forms O 𝛿- (slight negative charge) & H 𝛿+ (slight positive charge).

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10
Q

State 4 biologically important properties of water.

A

due to polarity & intermolecular H-bonds:
● Metabolite / solvent for chemical reactions in the body.
● high specific heat capacity.
● high latent heat of vapourisation.
● cohesion between molecules.

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11
Q

Explain why water is significant to living organisms.

A

● Solvent for polar molecules during metabolic reactions.
● Enables organisms to avoid fluctuations in core temperature.
● Cohesion-tension of water molecules in transpiration stream.

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12
Q

What are inorganic ions and where are they found in the body?

A

● Ions that do not contain carbon atoms.
● Found in cytoplasm & extracellular
fluid.
● May be in high or very low
concentrations.

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13
Q

Explain the role of hydrogen ions in the body.

A

● High concentration of H+ = low (acidic) pH.
● H+ ions interact with H-bonds & ionic bonds in tertiary structure of proteins, which can cause them to denature.

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14
Q

Explain the role of iron ions in the body.

A

Fe2+ bonds to porphyrin ring to form haem group in haemoglobin.

Haem group has binding site to transport 1 molecule of O2 around body in bloodstream.

4 haem groups per haemoglobin molecule.

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15
Q

Explain the role of sodium ions in the body.

A

Involved in co-transport for absorption of glucose & amino acids in lumen of gut (Topic 2.3).
Involved in propagation of action potentials in neurons (Topic 6.2).

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16
Q

Explain the role of phosphate ions in the body.

A

component of:
● DNA
● ATP
● NADP (Topic 5.1) ● cAMP (Topic 6.4)