Genetic Diversity can arise as a result of Mutation or during Meiosis - Genetics, Biodiversity and Classification Flashcards
What is a mutation?
An alteration to the DNA base sequence. Often arise spontaneously during DNA replication.
Why might a mutation not lead to change in the amino acid sequence?
● Genetic code is degenerate so mutation may end up coding for same amino acid as the original triplet. - you get the same product even if theres been a mutation
● Mutation may occur in intron.
What is a substitution mutation?
When a nucleotide in the DNA sequence is replaced by another. This is more likely to be a quiet mutation, meaning no change occurs in the amino acid sequence.
What is a deletion mutation?
When a nucleotide in the DNA sequence is lost. This is more likely to be harmful and significant, as it leads to a frame shift which means the entire amino acid sequence will be different.
What is a mutagenic agent? Give examples of this.
Factors that increase the rate of gene mutation. X-rays, UV light, gamma rays, certain chemicals e.g. in alcohol and tobacco.
What is a polyploidy chromosome mutation?
Where an individual has three or more sets of chromosomes instead of two.
What is chromosome non-disjunction?
When chromosomes fail to separate correctly in meiosis, resulting in gametes with one more or less chromosome than normal.
What happens during meiosis I?
- Homologous chromosomes pair to form bivalents.
- Crossing over (exchange of sections of genetic
material) occurs at chiasmata. - Cell divides into two. Homologous chromosomes
separate randomly. Each cell contains either maternal or paternal copy.
What is meiosis?
A form of cell division that produces four genetically different haploid cells (cells with half the number of chromosomes found in the parent cell) known as gametes.
How does meiosis differ from mitosis?
● Meiosis produces four genetically different cells with half the number of chromosomes as the parent cells.
● Mitosis produces two genetically identical cells with the same number of chromosomes as the parent cells.
What happens during meiosis II?
- Independent segregation of sister chromatids.
- Each cell divides again, producing 4 haploid cells.
Draw diagrams to show cells after each stage of meiosis.
check google
In which two ways does meiosis produce genetic variation?
- Crossing over during meiosis I 2. Independent assortment (random
segregation) of homologous chromosomes & sister chromatids
Result in new combinations of alleles.
