Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Clinical Chemistry (SEM1) > Lipids Clinical Correlations > Flashcards

Lipids Clinical Correlations Flashcards

You may prefer our related Brainscape-certified flashcards:
Periodic Table flashcards Chemistry 101 flashcards AP® Chemistry flashcards Organic Chemistry 101 flashcards
1
Q

Enumerate medicines that may raise TGs

A

Tamoxifen
Steroids
Beta-blockers
Diuretics
Estrogen
Birth control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Causes of high TGs

A

Obesity
Poorly controlled diabetes
Hypothyroidism
Kidney disease
Regularly eating more calories than you burn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How does kidney disease affect triglycerides?

A

Impaired renal function can lead to decreased clearance of Triglyceride from bloodstream. Possible hormonal influences like insulin resistance can lead to decreased activity of LPL.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Deficiency of beta-glucocerebrosidase
Macrophages look like crumpled paper “chicken scratch”

A

Gaucher’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Sphingomyelinase deficiency
Presence of FOAM CELLS

A

Neimann Pick Disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Hexosaminidase A deficiency
GM 2 ganglioside accumulation
Lysosomes with ONION SKIN

A

Tay-Sachs Disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Alpha-galactosidase A deficiency

A

Fabry Disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Beta-galactocerebrosidase deficiency that causes OPTIC ATROPHY and GLOBOID CELLS

A

Krabbe’s Disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

L-Iduronidase Deficiency

A

Hurler’s Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Iduronate Sulfatase Deficiency

A

Hunter’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Caused by LOW CIRCULATING APO B LEVELS
CM, VLDL, and LDL are absent in the plasma
Presented with Fat Malabsorption, Severe hypolipidemia, and retinitis pigmentosa

A

Abetalipoproteinemia (Bassen-Kornzweig Syndrome)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Characterized by LOW or UNDETECTABLE HDL in plasm

A

Tangier’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Independent Risk Factors

A

Triglycerides
HDL-C (for CHD)
Saturated Fatty Acids (for Atherosclerosis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Deficiency of Apo E-III

A

Beta-dyslipoproteinemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Excess insulin

A

Familial endogenous hypotriglyceridemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Post-heparin-activated lipoprotein lipase deficiency. Most common cause of fasting chlyomicronemia

A

Type I Hyperlipoproteinemia or Familial hypertriglyceridemia

17
Q

Increased beta lipoproteins
Deficient or mutated APO B-100 receptor

A

Type II Hyperlipoproteinemia or Familial Hypercholesterolemia

18
Q

Wherein, IDLs have equal amount of cholesterol and triglycerides

A

Familial Beta dyslipoproteinemia or Type III hypercholesterolemia

Clinical Chemistry (SEM1) (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions