Lipids Flashcards
Lipid: define
A highly water-insolube compound that is highly soluble in organic compounds, and possess hydrophobic regions
Fatty acids
building blocks of phosopholipids and glycolipids
nomenclature of fats
indicated by “oic”
two sites of unsaturation indicted by prefix “di, tri” oic
-decatrioic
double bonds in the fatty acids indicated in the name by
triangle with superscript; superscript indicates carbon on which the DB is located, and always attached to the following number. so triangle 9 indicates a double bond at carbon 9 to 10, but not 9 to 8.
also indicated by W symbole (omega)
W-5 would mean DB at carbon 5-6
Counting from the carboxylic
is how you would count the carbons, there’s an alpha and beta carbon immediately afterward
the terminal of the fatty acid is called the
W carbon, or distal end
Fatty acid characteristics
usually an even number of carbons, a lot are 16-18
carbons, configuration of the unsaturated fatty acid is cis
ionized at physiological pH
have a lower melting point the more double bonds present
the melting points of the saturated fatty acids increase with chain length
Non-essential FAs
Stearic acid (saturated) oleic acid (unsaturated)
w6 essential FA
Linoelic acid
arachidonic acid
w3 essential FA
alpha-linolenic acid
eicosapentaenoic acid
docosahexaenoic acid
what makes the membrane lipid of the archaeon so resilient to heat?
1) totally saturated fatty acids
2) an ester bond from acyl group (resists hydrolysis)
Major Membrane Lipids (3)
1) Phospholipids 2) glycolipids 3) cholesterol
Phospholipids: sphingomyelin, phosphoglyceride
Glycolipids: cerebroside
Phospholipid
Two fatty acids