Lipid Profile Flashcards

1
Q

What are lipid and how are they carried in blood

A

Lipid are water insoluble organic molecules that constituents cell and has energy production essentiality
They are carries by lipoproteins molecule

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2
Q

How are lipid transported in blood

A

Triacylgltcrides are transported by chylomicrins from their source and vldl from liver
Cholesterol is carried by hdl where it transports cholesterol to liver while ldl is carrying cholesterol to tissues

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3
Q

Lipid profile tests

A

Total cholesterol
Hdl cholesterol
LDL cholesterol
Extended through vldl cholesterol
Non hdl cholesterol
Some reports include cholesterol hdl ratio
Risk score

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4
Q

Total cholesterol

A

Measures all cholesterol in lipoprotein particle
Tc=ldl+hdl+vldl/1/5 of tag

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5
Q

LDL

A

Total cholesterol carried by DLL particle and is often called bad cholesterol as it carry cholesterol to tissues
Tc-hdl-vldl=ldl

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6
Q

Hdl

A

All cholesterol Carried by hdl and is often called good cholesterol as it carries cholesterol to liver
Hdl=tc-ldl-vldl

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7
Q

Vldl

A

Counted as one fifth of triacyglecerol and carries lipid from liver so importunate for preventing fatty liver

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8
Q

When is it requested

A

Part of routine checkup every 5 years
Patients at high risk
Medical conditions that could be associated with lipid profiling a pancreatitis
Children at high risk
Monitor response to medication as statins or alternation of lifestyle and diet

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9
Q

Risk factors

A

Obesity
Males of 45 age or more
Females of 50 age o more
Hypertension
Smoking
Diabetes
Cod history in family
Sedentary lifestyle
Junk food

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10
Q

How to prepare a patient for lipid profile test

A

Fasting for 12 to 14 hours no eating just drinking waterr

Blood sample taken from vein or by skin puncture

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11
Q

Test results are

A

Ldl:normally at 100 and high risk 160
Hdl: normally at 60 high risk if less than 35
Tags: are at 150 normally and high risk at 200
Total cholesterol:normally at 200 and risk if more than 240
Cholesterol to hdl ratio is 4:1 normally and high risk if more than 6:1

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12
Q

Why is ldl a risk factor

A

LDL is considered bad cholesterol as it deposits cholesterol in tisssues like vessel wall leading to narrowing of their lumen and thickness and hard walls might be called atherosclerosis

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13
Q

Causes of hypercholesterolemia

A

Diet rich in sfa, carbs and cholesterol
Drinking coffee and smoking
Diabetes
Obesity
Obstructive jaundice
Hyperlipoproteinemis
Hypothyrodism
Nephrosis

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14
Q

Causes of hypocholesterolemia

A

Prolonged starvation
Hyperthyroidism
Diet poor in sfa, carbs and cholesterol and rich in usfa
Liver diseases
Infections

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