Lipid Profile Flashcards
What are lipid and how are they carried in blood
Lipid are water insoluble organic molecules that constituents cell and has energy production essentiality
They are carries by lipoproteins molecule
How are lipid transported in blood
Triacylgltcrides are transported by chylomicrins from their source and vldl from liver
Cholesterol is carried by hdl where it transports cholesterol to liver while ldl is carrying cholesterol to tissues
Lipid profile tests
Total cholesterol
Hdl cholesterol
LDL cholesterol
Extended through vldl cholesterol
Non hdl cholesterol
Some reports include cholesterol hdl ratio
Risk score
Total cholesterol
Measures all cholesterol in lipoprotein particle
Tc=ldl+hdl+vldl/1/5 of tag
LDL
Total cholesterol carried by DLL particle and is often called bad cholesterol as it carry cholesterol to tissues
Tc-hdl-vldl=ldl
Hdl
All cholesterol Carried by hdl and is often called good cholesterol as it carries cholesterol to liver
Hdl=tc-ldl-vldl
Vldl
Counted as one fifth of triacyglecerol and carries lipid from liver so importunate for preventing fatty liver
When is it requested
Part of routine checkup every 5 years
Patients at high risk
Medical conditions that could be associated with lipid profiling a pancreatitis
Children at high risk
Monitor response to medication as statins or alternation of lifestyle and diet
Risk factors
Obesity
Males of 45 age or more
Females of 50 age o more
Hypertension
Smoking
Diabetes
Cod history in family
Sedentary lifestyle
Junk food
How to prepare a patient for lipid profile test
Fasting for 12 to 14 hours no eating just drinking waterr
Blood sample taken from vein or by skin puncture
Test results are
Ldl:normally at 100 and high risk 160
Hdl: normally at 60 high risk if less than 35
Tags: are at 150 normally and high risk at 200
Total cholesterol:normally at 200 and risk if more than 240
Cholesterol to hdl ratio is 4:1 normally and high risk if more than 6:1
Why is ldl a risk factor
LDL is considered bad cholesterol as it deposits cholesterol in tisssues like vessel wall leading to narrowing of their lumen and thickness and hard walls might be called atherosclerosis
Causes of hypercholesterolemia
Diet rich in sfa, carbs and cholesterol
Drinking coffee and smoking
Diabetes
Obesity
Obstructive jaundice
Hyperlipoproteinemis
Hypothyrodism
Nephrosis
Causes of hypocholesterolemia
Prolonged starvation
Hyperthyroidism
Diet poor in sfa, carbs and cholesterol and rich in usfa
Liver diseases
Infections