Lipid Lowering Drugs Flashcards
1
Q
high levels of free fatty acids contribute to
A
insulin resistance
2
Q
These drugs increase peripheral lipolysis and decrease hepatic triglyceride production
A
Fibric acid derivatives-Reduce levels of triglycerides
3
Q
Agonists of PPARa
A
fibric acid drugs
4
Q
nicotinic acid acts as (2 things)
A
agonist for GPR109A receptor, inhibitor of diacylglycerol acyltransferase
5
Q
Niacin/nicotinic acid does what
A
blocks triglyceride production
6
Q
cholesterol like acids that help solubilizing stuff
A
bile acid sequestrants
7
Q
Bile Acid Sequestrants increase what?
A
cholesterol metabolism
8
Q
Statins (inhibitors of HMG CoA Reductase)-do what?
A
inhibit production of cholesterol
9
Q
Cholesterol absorption inhibitors work by
A
Inhibit LDL formation-NPC1L1 transport protein is blocked
