Lipid Lowering Agents Flashcards

1
Q

What is the actions of antihyperlipidemic agents?

A

Lower serum levels of cholesterol and lipids

Prevent CAD

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2
Q

What are the unmodifiable risks factors for CAD

A

Genetic predisposition
Age
Gender

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3
Q

Which lipoprotein enters circulation as tightly packed cholesterol, triglycerides, and lipids?

A

LDLs

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4
Q

Which lipoprotein enters circulation as loosely packed lipids?

A

HDLs

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5
Q

What are the causes of hyperlipidemia

A

Excessive dietary intake of fats

Genetic alteration in fat metabolism leading to a variety of elevated fats in the blood

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6
Q

What are the drugs used to treat hyperlipidemia

A
Bile acid sequestrants 
HMG CoA inhibitors 
Fibrates 
Niacin
Cholesterol absorption inhibitors
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7
Q

Atorvastatin, lovastatin, pravastatin, rosuvastatin, and simvastatin are what kind of drugs?

A

HMG CoA inhibitors

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8
Q

What is the prototype for HMG CoA inhibitors

A

Atorvastatin

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9
Q

What is the prototype for cholesterol absorption inhibitors

A

Ezetimibe

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