Lipid Lowering Agents Flashcards
What is the actions of antihyperlipidemic agents?
Lower serum levels of cholesterol and lipids
Prevent CAD
What are the unmodifiable risks factors for CAD
Genetic predisposition
Age
Gender
Which lipoprotein enters circulation as tightly packed cholesterol, triglycerides, and lipids?
LDLs
Which lipoprotein enters circulation as loosely packed lipids?
HDLs
What are the causes of hyperlipidemia
Excessive dietary intake of fats
Genetic alteration in fat metabolism leading to a variety of elevated fats in the blood
What are the drugs used to treat hyperlipidemia
Bile acid sequestrants HMG CoA inhibitors Fibrates Niacin Cholesterol absorption inhibitors
Atorvastatin, lovastatin, pravastatin, rosuvastatin, and simvastatin are what kind of drugs?
HMG CoA inhibitors
What is the prototype for HMG CoA inhibitors
Atorvastatin
What is the prototype for cholesterol absorption inhibitors
Ezetimibe