Cardiotonic Agents Flashcards
What is congestive heart failure
Condition in which the heart fails to effectively pump blood around the body
What is the primary treatment for CHF
Involves helping the heart muscle to contract more efficiently to bring the system back into balance
What are three underlying problems in HF involving muscle function
The muscle could be damaged
The muscle could be forced to work too hard to maintain an efficient output
The structure of the heart could be abnormal
What is the composition of the sarcomere
Protein fibers
- thin actin fibers
- thick myosin fibers
What are the compensatory mechanisms
Decreased cardiac output
Cellular changes
What are the drugs used to treat CHF
Vasodilators (ACE inhibitors and nitrates)
Diuretics
Beta-Adrenergic Agonists
What do cardiac glycosides do?
Increase intracellular calcium, allowing more calcium to enter the myocardial cell during depolarization
What is the prototype for cardiac glycosides
Digoxin
Check apical pulse and hold digoxin if apical is less than 60
True