Antianginal Agents Flashcards
Fatty tumors in the intima of the heart vessels
Atheromas
Narrowing of the heart vessels
Atherosclerosis
Suffocation of the chest
Angina pectoris
Cells in the myocardium become necrotic and die
Myocardial infarction
What is a stable angina
No damage to heart muscle; basic reflexes surrounding the pain restore blood flow
Unstable angina
Episodes of ischemia occur even when at rest
Prinzmetal’s Angina
Caused by spasm of the blood vessels, not just by vessel narrowing
What are the actions of antianginal drugs
They improve blood delivery to the heart muscle by dilating blood vessels
Improve blood delivery to the heart muscle by decreasing the work of the heart
What are the types of antianginal drugs
Nitrates
Beta-Adrenergic Blockers
Calcium Channel Blockers
What are the routes for nitroglycerin
IV Sublingual Translingual spray Transmucosal spray Oral, SR Tablet Topical ointment Transdermal
What is the prototype for nitrates
Nitroglycerin
What is the prototype for beta blockers
Metoprolol
What is the prototype for calcium channel blockers
Diltiazem
