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atb > Lincosamida > Flashcards

Lincosamida Flashcards

1
Q

Exemplo de lincosamida

A

Clindamicina

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2
Q

Como age

A

Bacteriostatica por ligar a subunidade 50S ribossomo inobindo sintese proteica

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3
Q

Resistencia cruzada

A

Macrolideos pela alteracao receptor ribossomo

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4
Q

Faramacologia da clindamicina

A

Penetra bem pulmao, osso, bile

SNC NAO!

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5
Q

Cobertura da clindamicina

A

Gram (+) aerobios: S.aureus e S.epidermidis
S.pyogenes e um pouco S.pneumoniae,

ANAEROBIOS GRAM (+): BACTEROIDES FRAGILIS, fusobacterium, pepetoestreptococo, clostridium perfringens, corynebcaterium

EXCETO ENTEROCOCO e Clostridium diffice

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6
Q

Uao clinico

A

Infec pele e osteomiliete, abscesso

Genfivite, abscesso periodontal

Pneumonia aspirativa (+ atb gram neg), abscesso pulmonar

Gangrena

Abscesso hepatico

Difteria

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7
Q

Clindamicina Nao cobre bem

A
  • Gram (-) =Add ceftriaxone
  • ENTEROCOCO
  • CLOSTRIDIUM DIFFICILE
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8
Q

Evitar clindamicina na

A
  • Fasceite necrotizante perineal (founier)

- Colite pseudomembranosa

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9
Q

Doa abscessos só nao penetra em

A

Abscesso cerebral

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atb (16 decks)

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