Limbic

Question 1

What are the major components of the Circuit of Papez?

Answer 1

• Cingulate gyrus (entry)
• Cingulum
• Parahippocampal gyrus (entorhinal cortex)
• Dentate gyrus and hippocampus
• Fornix
• Mammillary body
• Anterior nucleus in thalamus

Question 2

What tract connects the entorhinal cortex to the hippocampus?

Answer 2

Perforant path

Question 3

What connects the fornix to the mammilary body?

Answer 3

post-commissural

Question 4

Korsakoff syndrome is a vitamin B deficiency that disrupts what?

Answer 4

Mamilo-thalamic tract

*Make up stories (confabulation)

Question 5

What tract connects the Anterior thalamus to the cingulate gyrus?

Answer 5

Thalamic-cortical tract

Question 6

What is the afferent pathway of the hippocmapal formation?

Answer 6

Perforant path and fornix (pre-commissural)

Question 7

What is the intrinsic pathway of the hippocampal formation?

Answer 7

Trisynaptic circuit

Question 8

What is the efferent pathway of the hippocampal formation?

Answer 8

Fornix (post-commisural)

Question 9

What are the 3 components of the trisynaptic circuit?

Answer 9

1-Perforant pathway
2-Mossy fibers
3-Schaffer collaterals

Question 10

What is the amygdala most commonly associated with?

Answer 10

Fear response

Question 11

What are the 3 major divisions of the Amygdala?

Answer 11

1-basolateral complex (fronto-temporal system, efferent)
2-Cortico-Medial system (olfactory, afferent)
3-Central nucleus (striatal, efferent)

Question 12

What are the major amygdala afferents?

Answer 12

• Lateral olfactory tract
• Prefrontal cortex
• Cingulum

Question 13

What are the major amygdala efferents?

Answer 13

• Amygdalofugal pathway (decision making)

- Stria terminalus (Autonomics)

Question 14

Bilateral lesions to the amygdala causes what?

Answer 14

Kluver-Bucy syndrome

*Docility, overeating, hyperphagia, hypersexuality