Life 103 Final Flashcards
3 components to circulatory systems
circulatory fluid, set of tubes, muscular pump
What class of organisms have a body cavity that is only 2 cells thick and that encloses a gastrovascular cavity (simplest form)?
Cnidarians
Small and simple organisms use what in place of a circulatory system?
Passive Diffusion
The fraction of the total blood volume occupied by red blood cells
Hematocrit
2 types of leukocytes
Granular and Agranular
What cells are classified as Granular leukocytes?
Neutrophils, eosinophils, and basophils
What cells are classified as Agranular leukocytes?
Monocytes and lymphocytes
What is Hematopoiesis
blood cell production
2 types of stem cells
Lymphoid and Myeloid
What is Erythropoietin?
stimulates the production of erythrocytes
What does Somatic NS do?
stimulates skeletal muscles
What does Autonomic NS do?
stimulates smooth and cardiac muscles, as well as glands
3 types of neurons
sensory, motor, interneurons
Function of sensory neurons?
carry impulses to central nervous system
Function of motor neurons?
carry impulses from CNS to effectors (muscles and glands)
Function of interneurons?
provides more complex reflexes and associative functions
Basic components of neurons
cell body, dendrites, and axon
Enlarged part of a neuron containing nucleus
Cell Body
Short part of a neuron, cytoplasmic extensions that receive stimuli
Dendrites
Single, long extension of a neuron that conducts impulses away from cell body
Axon
Produce myelin sheaths surrounding axons.
Schwann cells and oligodendrocytes
Support neurons both structurally and functionally
Neuroglia
Negative pole
cytoplasmic side
Positive pole
extracellular fluid side
3 things that make up the interior of a cell in the nervous system
- Sodium-potassium pump
- ion leakage channels
- differential distribution of other ions and molecules across the pm
Balance between diffusional force and electrical force
Equilibrium Potential
2 types of synapses
Presynaptic and postsynaptic
Function of presynaptic cell
transmits action potential
Function of postsynaptic cell
receives action potential
Neurotransmitters (4)
Acetylcholine, Amino Acids, Biogenic Amines, Neuropeptides
Type of Neurotransmitter:
- Crosses the synapse between a motor neuron and a muscle fiber
- Binds to receptor in the postsynaptic membrane
- Causes ligand-gated ion channels to open
- Stimulates muscle contraction
Acetylcholine
Function of Acetylcholinesterase
Breaks down ACh and causes muscle relaxation
2 types of amino acids that are involved in neurotransmitters
Glutamate, Glycine and GABA
Role of Glutamate in nervous system
Major excitatory neurotransmitter in the vertebrate CNS
Role of Glycine and GABA in the nervous system
are inhibitory neurotransmitters
Open ligand-gated channels for Cl-
Produce a hyperpolarization called an inhibitory postsynaptic potential (IPSP)
4 types of Biogenic Amines in the nervous system
Epinephrine, Norepinephrine Dopamine, Serotonin
Function of epinephrine and norepinephrine in the nervous system
are responsible for the “fight or flight” response
Function of dopamine in the nervous system
is used in some areas of the brain that control body movements
Also acts outside the nervous system as a paracrine messenger and vasodilator
Function of serotonin in the nervous system? What hormone is it coupled with?
Is involved in the regulation of sleep
Coupled with hormone melatonin
Neuropeptides involved in the nervous system
Substance P and Nitric Oxide
Function of Substance P in the nervous system
(small peptide) is released from sensory neurons activated by painful stimuli
Function of Nitric Oxide in the nervous system
Causes smooth muscle relaxation
Increased signal speed in an axon can be caused by:
increased diameter of axon and saltatory conduction via nodes of Ranvier
2 ways that the membrane can reach the threshold voltage
Spatial Summation and Temporal Summation
secretes hormones that coordinate slower but longer-acting responses including reproduction, development, energy, metabolism, growth, and behavior
Endocrine system
conveys high-speed electrical signals along specialized cells called neurons; these signals regulate other cells
Nervous System
How many human hormones have been identified?
70
are chemical signals that are secreted into the circulatory system and communicate regulatory messages within the body
Hormones
What do exogenous chemicals do to hormone signaling?
interfere with hormone signaling
Secreted Chemicals Include:
- Hormones
- Local Regulators
- Neurotransmitters
- Neurohormones
- Pheromones
Have ducts and secrete substances onto body surfaces or into body cavities
Ex: tear ducts, sweat glands, salivary glands, liver, pancreas, mammary glands, stomach
Exocrine glands
Examples of Exocrine Glands
tear ducts, sweat glands, salivary glands, liver, pancreas, mammary glands, stomach
How do hormones work?
Chemical signals bind to receptors on target cells
Only target cells respond to the signal
Hormone is expressed as needed
are chemical signals that travel over short distances by diffusion
Local Regulators
What do local regulators help to do?
Help regulate blood pressure, nervous system function, and reproduction
2 Groups of Local Regulators
Paracrine and Autocrine
Which group of local regulators?
Signals act on cells near the secreting cells
Paracrine Signaling
Which group of local regulators?
Signals act on the secreting cell itself
Autocrine Signaling
Cell to cell signaling driven by nervous system
Synaptic signaling
Chemical signals released from the body and used to communicate with other individuals in the species
Mark traits to food sources, warn of predators, and attract mates
Pheromones
3 major classes of hormones in vertebrates
Polypeptides (proteins and peptides)
Amines (derived from amino acids)
Steroid hormones
Pass easily through cell membranes
Diffuse across cell membranes, travel in bloodstream bound to transport proteins, and diffuse through the membrane of target cells
Lipophilic Hormones
(Polypeptides and Amines) Do not
Are secreted by exocytosis, travel freely in the bloodstream, and bind to cell-surface receptors
Hydrophilic Hormones
What factor of a hormone correlates with the location of receptors inside or on the surface of target cells?
Solubility
Binding of a hormone to its receptor initiates a signal transduction pathway leading to responses in the cytoplasm, enzyme activation, or a change in gene expression.
Water Soluble Pathway
Lipid-soluble hormone is usually a change in gene expression
Steroids, thyroid hormones, and the hormonal form of vitamin D enter target cells and bind to protein receptors in the cytoplasm or nucleus.
Lipid Pathway
Act as transcription factors in the nucleus, regulating transcription of specific genes
Protein-receptor complexes
Where is Vitamin D found?
Formed in the skin of vertebrates
Feathers and Fur block the skin
Oily secretions on fur generate the vitamin and licking absorbs it
Where is Vitamin D transported and what is it converted into?
Transported to the liver
Converted into physiological active form
What does Vitamin D regulate?
Calcium and phosphate in the blood
Cell proliferation and apoptosis
Neuromuscular function