Leukaemia Flashcards
1
Q
Key features of acute leukaemia
A
Immature blast cells >20% in BM
BM failure
Organ infiltration
2
Q
Summarise the aetiology of acute leukaemia
A
3
Q
Acute leukaemia Dx
A
4
Q
Compare epidemiology and clinical features of ALL and AML
A
5
Q
Compare Ix for ALL and AML
A
6
Q
Compare Mx for ALL and AML
A
7
Q
Compare common mutations for ALL and AML
A
8
Q
Presentation of CML
A
9
Q
Key drug for CML
A
Imatinib
10
Q
CML Ix
A
FISH - Ph+
PCR - BCR-ABL
WCC - high neutrophils and basophils
Hypercellular BM + immature myelocytes and mature granulocytes in blood
11
Q
Summarise the 3 phases of CML
A
12
Q
Summarise the 3 phases of CML
A
13
Q
Summarise key features of CLL
A
14
Q
CLL Ix
A
15
Q
CLL staging
A
16
Q
CLL Mx
A
