Bleeding Disorders Flashcards
Compare the two main types of bleeding disorder
What vascular defects cause disordered bleeding?
Summarise the causes of platelet disorders
Compare acute and chronic ITP
Summarise haemophilia A
Summarise haemophilia B
Summarise vWD
Summarise DIC
Summarise how liver disease can affect clotting
Summarise vitamin K deficiency
High INR, High aPTT, normal PT, normal Plt, High TT
Heparin
Activates antithrombin III → inactivates 2, 9 and 10 (intrinsic and common pathway)
High INR, High aPTT, normal PT, low Plt, High TT
Heparin induced thrombocytopaenia
High INR, High aPTT, High PT, low Plt, High TT
DIC
High INR, High aPTT, High PT, normal/low Plt, normal/high TT
Liver disease
N INR, N aPTT, N PT, low Plt, high TT
Thrombocytopaenia