Lesson 6 Flashcards

1
Q

Is limiting the agent/pathogen’s access to people

A

Laboratory Biosafety

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2
Q

The containment principles, technologies and practices that are implemented to prevent the unintentional exposure to pathogens and toxins, or their accidental release.

A

Laboratory Biosafety

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3
Q

The protection, control, and accountability for valuable biological materials within laboratories, in order to prevent their unauthorized access, loss, theft, misuse, diversion, or intentional release.

A

Laboratory Biosecurity

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4
Q

Is limiting people’s access to the agent/pathogen.

A

Laboratory Biosecurity

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5
Q

Date:
First scientific director of ______ (Fort Detrick)

A

Date: 1943
Ira L. Baldwin, Camp Detrick

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6
Q

Date:
US President Franklin Roosevelt tasked Baldwin to establish __________ for defensive purposes during the Cold War

A

Date: 1943
US biological weapons program

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7
Q

Date:
The biological weapons program was terminated by US President _______

A

Date: 1969
Richard Nixon

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8
Q

After the Second World War, Camp Detrick was designated a permanent installation for _________

A

Biological research and development.

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9
Q

Date:
Began of the _______ of smallpox

A

Date: 1967
Intensified Eradication Program

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10
Q

Designed modifications for biosafety at
Camp Detrick

A

Newell A. Johnson

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11
Q

Date:
Formation of _______ (ABSA)

A

Date: 1984
American Biological Safety Association

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12
Q

Date:
England and South Africa either destroyed the stocks or transferred them to other approved labs. Therefore, only two locations
where variola virus is officially stored.

A

Date: 1984
Center for Disease Control and Prevention (CDC)
State Research Center of Virology and Biotechnology VECTOR (SRCVB VECTOR)

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13
Q

Date:
The ________ agreed to reduce the number of laboratories holding stocks of _____ virus (United States, England, Russia, and South Africa)

A

Date: 1967
World Health Assembly, Variola Virus

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14
Q

Published by ______ , and introduced the concept of establishing ascending levels of containment associated with risks in handling groups of infectious microorganisms that present similar
characteristics

A

Classification of Etiologic Agents on the Basis of Hazard

Published by: CDC

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15
Q

Explained in detail the microbiological practices, equipment, and facility necessarily corresponding to four ascending levels of physical containment

A

NIH Guidelines for Research Involving Recombinant DNA Molecules

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16
Q

Date:
Laboratory Biosafety Manual

A

Date: 1983
Laboratory Biosafety Manual

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17
Q

Date:
Marked the development of the practice of laboratory biosafety

A

Date: 1984
Biosafety in Microbiological and Biomedical Laboratories

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18
Q

Date:
Established the model of biosafety containment levels with certain agents which increased the biosafety levels for biological agents that
pose risk to human health.

A

Date: 1984
Biosafety in Microbiological and Biomedical Laboratories

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19
Q

Director of_______; recognized as one of the pioneers of biosafety

A

Arnold Wedum, Industrial Health and Safety

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20
Q

Ensures that the proper equipment and facility controls are in place based on the specified biosafety level of the laboratory.

A

Biosafety Officers

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21
Q

Together with Wedum, analyzed multiple epidemiological studies of laboratory-based outbreaks

A

Morton Reitman

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22
Q

Date:
Members of the ___________ commune purchased a strain of _______ from a medical supply company in Seattle, Washington

A

Date: 1980
Rajneeshee, Salmonella

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23
Q

Date:
At least 5 envelopes containing _____________ were mailed to US senators and media organizations

A

Date: 2001
(Amerithrax) Bacillus anthracis spores (etiologic agent of anthrax)

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24
Q

(USAMRIID)

A

United States Army Medical Research Institute for Infectious Disease

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25
Q

Through rats containing flea; causes bubonic plague

A

Yersinia pestis

26
Q

Causes cholera through contaminated water or food

A

Vibrio cholerae

27
Q

Causes tularemia through ticks

A

Francisella tularensis

28
Q

Date:
To monitor the transfer of a select list of biological agents from one facility to
another

A

Date: 1996
Select Agent Regulations

29
Q

(Singapore)

A

Biological Agents and Toxins Act

30
Q

(South Korea)

A

Act on Prevention of Infectious Diseases

31
Q

(Japan)

A

Infectious Disease Control Law

32
Q

Regional professional society for biosafety and biosecurity founded in _____

A

Date: 1984
American Biological Safety Association (ABSA)

33
Q

Promotes biosafety as a scientific discipline and provides guidance to its members on the regulatory regime present in North
America

A

American Biological Safety Association (ABSA)

34
Q

Date:
Group founded in _____ that acts as a professional society for biosafety professionals in the Asia-Pacific region.

A

Date: 2005
Asia-Pacific Biosafety Association (A-PBA)

35
Q

Active members of the International Biosafety Working Group are required to directly contribute to the development of the best
biosafety practices

A

Asia-Pacific Biosafety Association (A-PBA)

36
Q

Date:
A non-profit organization founded in ___
Aims to provide a forum for discussions and debates on issues of concern and to represent those working in the field of biosafety.

A

Date: June 1996
European Biological Safety Association (EBSA)

37
Q

Focuses on encouraging and communicating among its members information and issues on biosafety and biosecurity as well as emerging legislation and standards

A

European Biological Safety Association

38
Q

Non-government and non-profit association that works to serve the emergent concerns of biological risk management in various
professional fields such as in the health, agriculture, and technology
sectors throughout the country

A

Biological Risk Association Philippines

39
Q

Tag line of BRAP

A

Assess Mitigate Monitor

40
Q

An environmental health engineer working for the Dow Chemical Company containment systems products

A

Charles Baldwin

41
Q

Created the _______ symbol used in labeling biological materials carrying significant health risks.

A

Charles Baldwin, Biohazard symbol

42
Q

Classification of Microorganisms (WHO)

A

✓ Agent’s pathogenicity
✓ Mode of transmission
✓ Host range
✓ Availability of preventive measures and effective treatment

43
Q

No or low individual and community risk

A

Risk group 1

44
Q

Includes microorganism, or material containing microorganisms, that are
already present in the environment, and are unlikely to cause human, plant,
or animal disease, disrupt a region or an industry.

A

Risk group 1

45
Q

Moderate individual risk, and low/limited community risk

A

Risk group 2

46
Q

Includes microorganism, or material containing microorganisms, that can
cause human, plant, or animal disease, but is unlikely to be a serious hazard
to laboratory workers, community, livestock, or the environment.

A

Risk group 2

47
Q

High individual risk, and limited to moderate community risk

A

Risk group 3

48
Q

Includes microorganism, or material containing microorganisms, that usually
causes serious human, plant, or animal disease, and may present a serious
risk to laboratory workers.

A

Risk group 3

49
Q

It could present a risk if spreads in the community, in a region, to the livestock
industry or the environment, but there are usually effective preventive
measures or treatment available.

A

Risk group 3

50
Q

High individual and community risk

A

Risk group 4

51
Q

Includes microorganism, or material containing microorganisms, that are known to produce life-threatening diseases to humans or animals.

A

Risk group 4

52
Q

It represents a significant risk to laboratory workers and may be readily
transmissible from one individual to another; effective treatment and
preventive measures are not usually available.

A

Risk group 4

53
Q

CDC categorized laboratories based on:

A

✓ Design features and construction
✓ Containment facilities
✓ Equipment
✓ Practices
✓ Operational procedures

54
Q

Suitable for work involving viable microorganisms that are known not
to cause disease in humans.

A

Biosafety level 1

55
Q

Basically designed for laboratories that deal with indigenous
moderate-risk agents present in the community.

A

Biosafety level 2

56
Q

It is most appropriate among undergraduate and secondary
educational training and teaching laboratories

A

Biosafety level 1

57
Q

It observes practices, equipment, and facility design that are
applicable to clinical, diagnostic, and teaching laboratories consequently observing good microbiological techniques.

A

Biosafety level 2

58
Q

It is appropriate when work is done with human blood, body fluids,
tissues, or primary human cell lines where there is uncertain presence
of infectious agents.

A

Biosafety level 2

59
Q

All procedures where infectious aerosols or splashes may be created
are conducted in biosafety cabinets or other physical containment
equipment.

A

Biosafety level 2

60
Q

Designed for laboratories that deal with indigenous or exotic agents
with a potential for respiratory transmission, and that may cause serious and potentially lethal infection.

A

Biosafety level 3

61
Q

Laboratory required when working with dangerous and exotic agents
that pose high individual risks of life-threatening diseases that may be
transmitted via the aerosol route, for which there are no available
vaccines or treatment.

A

Biosafety level 4

62
Q

The laboratory worker’s complete isolation from aerosolized infectious
materials is accomplished primarily by working in a Class III biosafety
cabinet or in a full-body, air-supplied positive-pressure personnel suit

A

Biosafety level 4