Lesson 4 Pt. 2 Flashcards
Greatest exposure occurs during placental separation which causes massive production of anti RH abs during _______
1st 72 hours postpartum
Fetal bone marrow produces immature RBCs causing
Erythroblastosis Fetalis
RBC destruction causes massive production and accumulation of bilirubin as the immature liver is unable to clear them from body leading to:
Hyperbilirubinemia
Kernicterus
What do you call the “RBC destruction causes massive production and accumulation of bilirubin as the immature liver is unable to clear them from body leading to Hyperbilirubinemia and
Kernicterus”
Erythroblastosis Fetalis
Fetal Complication of Erythroblastosis Fetalis
Anemia
Spleenomegaly and hepatomegaly
Hyperbillirubinemia
Hydrops fetalis
Stillbirth
As organ not perfused properly, the heart will eventually decompensate; fluid builds up resulting to edema
Hydrops fetalis
Prevention for Pre-Natal Screening:
Blood typing and Rh typing
Coombs test
Give RhoGAM
Coombs Test : what indicates sensitization
> 1:16
What is an INDIRECt Coombs Test
Maternal serum
What is an example of DIRECT Coombs Test
Cord blood
RhoGam means
Rhod Gamma Globulin
Rhogam should be given to all “Rh - women” who:
Have delivered Rh+ fetus
Have had untypeable pregnancies
Have receive ABO compatible Rh+ blood
Have had invasive procedure
Example of untypeable pregnancies
Ectopic pregnancies
Still birth
Abortion
Example of invasive procedure
Amniocentesis
Chorionic Villi Sampling
Amniocentensis should be every ______
2 wks beginning
When to start monitor billirubin
26 wks
Percutaneous umbilical blood sampling at _______ wks if biliirubin is high
18-20 wks
Intrauterine Blood Fetal Transfusion at _______
10 day to 2 week interval
Until 34-36 wks
It can be caused by placental transfer or direct contact with maternal blood during birth
HIV AND AIDS
A slowly replicating retrovirus and has atleast 2 division
HIV
Two main divisions of HIV
HIV-1
HIV-2
The virus acts by attacking the lymphoreticular system, in particular CD4 beseing helper T lymphocytes
HIV
Etiologic Agent for HIV
Retrovirus
T-lymphocytes is also known as
T4 cells
It regulates the normal immune response
CD4 Cells
Early symptoms of HIV
Fatigue
Anemia
Diarrhea
Weight loss
Lymphadenopathy
Night sweats
Production of antibodies vs HIV, happen in 6 weeks to 1 year
Seroconversion
Asymptomatic period of HIV is
3-11 yrs
Usually CD4 count of HIV
<200 cells/mm3
