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Histo lab > Lesson 3 > Flashcards

Lesson 3 Flashcards

1
Q
  • Most diverse group of tissues
  • Supports and binds tissues for all organs
A

CONNECTIVE TISSUE

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2
Q
  • Loose and fluid type of embryonic tissues
  • Common origin of all connective tissues
A

MESENCHYME

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3
Q
  • can be situated in any way and can move from place to place.
  • small spindle-shaped (tapered ends) cells with large nuclei (multipotent stem cells – it can differentiate as progenitor cell for cartilage, bone, and blood)
    o Spindle-shaped - similar appearance with Trichuris trichiura
     Unlike the Epithelial cells which have fixed and neatly arranged in sheets
A

MESENCHYMAL CELLS

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4
Q

avascular (no blood supply)

A

o Cartilage

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5
Q

vascular (has blood supply)

A

o Dense irregular tissue in skin

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6
Q
  • Its cells are separated by a large amount of Intercellular space
A

CONNECTIVE TISSUES

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7
Q
  • Non-living component of connective tissues
  • Transparent and colorless (water)
  • Also known as “Inert matrix”
    1. Ground Substance
    2. Fibers
A

Extracellular Matrix (ECM)

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8
Q
  • Watery, rubbery, unstructured material that fills the spaces between cells
    o Highly hydrated; bounded by water
  • Protects the cells in the extracellular matrix
  • Flexible - made of starch, protein molecules and water
A

GROUND SUBSTANCE

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9
Q

anchors the framework of ground substance

A

o Proteoglycans

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10
Q

key proteoglycan in all basal laminae

A

 Perlecan

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11
Q

most abundant in articular cartilage

A

 Aggrecan

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12
Q

sprouts from proteoglycans

A

o GAG or Glycosaminoglycans

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13
Q

 Binding sites for cell surface integrins and macromolecules

A

o Multi-adhesive glycoproteins

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13
Q

largest, most ubiquitous (most known) of all GAGs

A

 Hyaluronan

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14
Q

strongest and most abundant type, tough and flexible.
 A major product of fibroblast

A
  1. Collagen
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15
Q
  • Provide support and structure to the otherwise shapeless ground substance
A

FIBERS

16
Q

longer and thinner which form a branching framework within the matrix.
 Made of protein elastin - allows them to stretch and recoil
 Found in the skin, lungs and blood vessel walls

A
  1. Elastic Fibers
17
Q

 Short, finer collagen fibers (type 3) with an extra coating of glycoprotein.
 Forms a delicate, sponge-like networks that cradle and support the organs.
 Found in organs and immune system

A
  1. Reticular Fibers
18
Q
  • Literally means “forming”
  • Stem cells or immature cells
  • Undergoes mitosis to replicate themselves
  • Has different types with different functions
  • Once they mature they transition from -blast to -cyte
A

BLASTS

19
Q
  • blast cells of the bone tissue
  • Osteocytes – mature cells
A

OSTEOBLAST

19
Q
  • blast cells of cartilage
  • Chondrocytes – mature cells
A

CHONDROBLAST

20
Q
  • Most diverse group in the tissue family
  • To differentiate: based on the amount of fibers in the ground substance
A

CONNECTIVE TISSUE PROPER

21
Q
  • provide immune defense for connective tissues, phagocytize bacteria, foreign materials and dead cells
  • capable of phagocytosis
  • also known as histiocyte
A

MACROPHAGES

22
Q
  1. Mesenchyme
A

embryo, fetus

23
Q

tendon/ligament
1. Regular
2. Irregular
3. Elastic

A
  • Dense Connective Tissue
24
Q
  • Have fewer fibers, and more cells and more ground substance.
A

LOOSE CONNECTIVE TISSUE

25
Q

Wharton’s jelly or umbilical cord (composed of hyaluronan)

A
  1. Mucoid
26
Q

subcutaneous tissue (dermis)

A
  1. Adipose
27
Q

bone marrow, lymph node, spleen

A
  1. Reticular
28
Q
  • Most common loose connective tissue
  • Found all over the body
  • Under the epithelial tissues and wrapped around the organs
  • It has loose and random arrangement of fibers
  • Few fibroblast cells
  • Has a lot of open space/ground substance
A

AREOLAR CONNECTIVE TISSUE

29
Q
  • Fat tissue
  • Adipocytes - Fat cells
  • Fats push out nucleus
  • Main lipid – triglyceride
  • Is not mostly ground substance
  • Holds your blood cells in place in many of the blood forming organs
  • Similar to areolar tissue but with a woven mass of reticular fibers instead of collagen and elastin fibers
A

ADIPOSE CONNECTIVE TISSUE

30
Q

tendon, stroma of cornea
* Compact collagen fibers are stacked neatly in regular rows

A
  1. Regular
31
Q

dermis, capsules of organs
* Collagen fibers are not stacked regularly in rows
* Fibers are thicker and arranged erratically
* Found wherever tension might be exerted in lots of different directions such as the leathery dermis under the skin

A
  1. Irregular
32
Q
  • Collagen with interwoven elastic fibers
  • Found in places in the body that requires more elasticity and rigidity such as around the joints
  • Connecting the vertebrae so the spine can curve and twist
  • Component of arteries - to provide support and flexibility
A
  1. Elastic
33
Q
  • Dense connective tissue
  • Connects your bone to muscle and muscle to muscle
  • BM & MM
A

TENDON

34
Q
  • Dense connective tissue
  • Connects your bone to bone
  • BB
A

LIGAMENT

Histo lab (8 decks)

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