LESSON 3 Flashcards
2 principal kinds of cells
neuroglia
neuron
the “nerve glue” or the cells that support the neurons of the CNS
NEUROGLIA
-glia means
glue
Function of neuroglia
support
insulation
nutrition
protection
6 types of neuroglia
SESAMO:
schwann cells
ependymal
satellite cells
astrocytes
microglia
oligodendrocytes
astro means
star
-cyte means
cell
- star-shaped cells with many processes
astrocytes
2 types of astrocytes
protoplasmic
fibrous
- astrocytes with many short branching processes (location: gray matter)
protoplasmic astrocytes
- long unbranched processes (location: mainly
white matter)
fibrous astrocytes
- help to maintain the appropriate chemical environment for the generation of nerve impulses.
astrocytes
- Also play a role in learning and memory by influencing the formation of neural synapses
astrocytes
Help forms the Blood Brain Barrier
astrocytes
it restricts the movement of substances between the blood and interstitial fluid of the CNS
blood-brain barrier
3 components of BBB
- astrocytes and astrocytic feet/processes
- capillary basement membrane/basal lamina with embedded pericytes
- tight junction between overlapping endothelial cells of the brain capillaries
encircle the capillaries secrete chemicals that maintain the permeability characteristics of the tight junctions
astrocytes and astrocytic feet/processes
cover the basal lamina of the endothelium and
contribute to the structural integrity of the BBB
pericytes
Substances may cross the BBB primarily by two mechanisms:
paracellular transport
transcellular transport
oligo means
few
o-dendro means
trees
these resemble astrocytes but are smaller and contain fewer processes
oligodendrocytes
Give support by forming semi-rigid connective tissue rows between neurons in the CNS
oligodendrocytes
Produce phospho-lipid for the myelin sheath around axons of neurons in the CNS - responsible for forming and maintaining the myelin sheath around CNS axons
oligodendrocytes
These neuroglia are small cells with slender processes that give off numerous spinelike projections
microglia/brain macrophages/microglial cells
act as macrophages
microglia
epen means
above
-dym means
garment
cuboidal to columnar cells arranged in a single layer that possess microvilli and cilia
ependymal cells
FUNCTION:
a. Form a continuous epithelial lining for the ventricles of the brain & the central canal of the spinal cord
b. Assist in the formation & circulation of CSF in the ventricles of the brain & the central canal of the spinal cord
ependymal cells
outer nucleated cytoplasmic layer of the schwann cell which encloses the myelin sheath
neurolemma
participate in axon regeneration, which is more easily
accomplished in the PNS than in the CNS
Schwann cells
- form myelin sheath around axons of neurons of the peripheral nervous system
schwann cells
These flat cells surround the cell bodies of neurons of PNS ganglia
satellite cells
Function:
a. Provides structural support,
b. Regulate the exchanges of materials between neuronal cell bodies and interstitial fluid
satellite cells
e basic functional unit of the nervous system. They are the primary cells of the nervous system
neuron/nerve cells
Its primary function is the conduction of
impulses from one part of the body to another
neuron/nerve cells
Nerve impulses travel at speeds ranging
0.5-130 meters per second (1-290 mi/hr)
fuel source for neurons
glucose
fuel source for neurons
glucose
fuel source for neurons
glucose
highly specialized cells
neuron
The main portion of a neuron and contains a nucleus surrounded by cytoplasm
cell body
The main portion of a neuron and contains a nucleus surrounded by cytoplasm
cell body
- clusters of rough ER and free ribosomes
- site of protein synthesis in neurons
Nissl bodies
- clusters of rough ER and free ribosomes
- site of protein synthesis in neurons
Nissl bodies
cytoskeleton of the cell body that gives cell shape and support
neurofibril
assist movement of material to and from the cell body and axon
microtubules
assist movement of material to and from the cell body and axon
microtubules
assist movement of material to and from the cell body and axon
microtubules
- yellow brown granules in the cytoplasm
- can be found in aging neurons that is result of accumulated neuronal lysosomes
Lipofuscin
- yellow brown granules in the cytoplasm
- can be found in aging neurons that is result of accumulated neuronal lysosomes
Lipofuscin
- yellow brown granules in the cytoplasm
- can be found in aging neurons that is result of accumulated neuronal lysosomes
Lipofuscin
- short with often highly branching cytoplasmic extension
- the receiving or input portions of a neuron
dendrites
- long thin, cylindrical projection that joins the cell body at a cone-shaped elevation called axon hillock
axon
part of the axon closest to the axon hillock
initial segment
cytoplasm of axon
axoplasm
plasma membrane surrounding the axoplasm
axolemma
side branches along the length of an axon, typically at a right angle to the axon
axon collateral
a multi-layered lipid and protein covering of an axon
which insulates the axon and increases the speed of nerve impulse conduction
myelin sheath
impulse propagation/transmission that skips
from node to node, providing rapid transmission of impulses
saltatory conduction
unmyelinated gaps between segments of the myelin
sheath
node of ranvier
fine processes where the axon/axon collaterals end
axon terminal/axon telodendria
bulb-shaped structures at the tips of axon terminal
synaptic end bulbs
membrane-enclosed sacs of the synaptic end bulbs
which store neurotransmitters
synaptic vesicles
Classification of neurons according to structure:
Unipolar, bipolar neurons, multipolar neurons
-most common
-multiple dendrites, one axon
-example: neurons in the CNS
multipolar neurons
- have 2 distinct processes: one main dendrite and one axon arising from the cell body
- very rare types of neurons
- example: sensory receptor cells in some special sense organs
bipolar neurons
- are made up of only one projection from the cell body
- are made up of only one projection from the cell body
- short neurons
unipolar
classification of neurons according to function
- sensory/afferent
- motor/efferent
- are structurally multipolar, carry impulses from the CNS
to other parts of the body to effectors (muscles and glands) in the periphery through cranial or spinal nerves
motor neurons
- They receive stimuli/info from either the internal or external environment thru the AFFERENT/SENSORY nerve pathways
sensory neuron
- that are also structurally multipolar
- interprets/process the information received in order to determine appropriate response to take
interneuron/connecting neurons
- a universal term for any neuronal process (extension)
whether dendrite or axon, that emerges from the cell body of a neuron.
nerve fiber
bundle of many nerve fibers
nerve
cluster of cell bodies in the CNS
nuclei
small groups of nervous tissue containing primarily of cell bodies which are found in the PNS
GANGLIA
bundle of nerve fibers in the CNS
tract
connective tissue sheaths:
- endoneurium
- perineurium
- epineurium
- are thin connective tissue sheath that surrounds each nerve fiber/axon
endoneurium
- surrounds bundles of axons known as fascicles
perineurium
- surround an entire nerve
epineurium
- conduct nerve impulses from the skin, skeletal
muscles and joints to the CNS
General somatic afferent fibers
- conduct nerve impulses from the CNS to the skeletal muscle
General somatic efferent fibers
- conduct nerve impulses from the viscera and blood vessels to the CNS
General Visceral Afferent Fibers
- convey nerve impulses from the CNS TO HELP CONTRACTIONS OF SMOOTH AND CARDIAC MUSCLES AND RATE OF SECRETION OF GLANDS
General Visceral Efferent fibers