Lesson 12 - Endogenous Pacemakers and Exogenous Zeitgebers Flashcards
What are endogenous pacemakers?
Internal biological rhythms
What are exogenous zeitgebers?
External cues and factors
E.g. light
What is the role of endogenous pacemakers and exogenous zeitgebers?
To reset our biological rhythms every day
What is the most important endogenous pacemakers?
SCN
What is the SCN?
A tiny cluster of nerve cells in the hypothalamus
What role does the SCN play?
An important role in generating circadian rhythms
What does the SCN do?
Acts as the master clock
Linking other brain regions controlling sleep and arousal
And controlling all other biological clocks throughout the body
What do the neurons in the SCN do?
Neurons in the SCN synchronise with each other
So that their target neurons elsewhere in the body receive time-coordinated signals
Why are the peripheral clocks controlled by the SCN?
They can maintain a circadian rhythm but not for very long
Why can the SCN maintain a circadian rhythm?
It has a built in circadian rhythm
Only needs resetting when external light levels change
How does the SCN receive information about light levels?
Optic nerve
What happens when the biological clock is running slow?
Morning light shifts the clock
What does the SCN also regulate?
Regulates the manufacture and secretion of melatonin in the pineal gland
Via the interconnecting neural pathway
How does the SCN control melatonin levels?
SCN sends a signal to pineal gland -> increase production and secretion of melatonin at night and decrease it as light levels increase in morning
How does melatonin work?
Induces sleep by inhibiting the brain mechanisms that promote wakefulness