Leptospira Flashcards

1
Q

natural course of mild uncomplicated leptospirosis

A

spontaneous resolution within 7 –10 days without sequelae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

jaundice, acute kidney injury, hypotension, and hemorrhage—mostcommonly involving the lungs

A

Weil’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

cardiac involvement in lep

A

nonspecific ST and T wave changes but also asright-bundle-branch block and right- and/or left-sided ventricular dilation indicating myocarditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

gold std lepto

A

microscopic agglutination test (MAT)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

neuro findings lepto

A

aseptic meningitis

hypo- or areflexia, especially of the legs.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

primary renal pathophysiologic lesion in acute leptospirosis,

A

Primary injury of the proximal convoluted tubules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

diagnostic mainstay in leptospirosis.

A

Serologic assays

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Culture leptospira

A

blood and CSF during the first 7–10 days of illness and from urine beginning in the second week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Rx mild leptospirosis

A

Doxycycline (100 mg PO bid) or Amoxicillin (500 mg PO tid) or Ampicillin (500 mg PO tid)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Rx Moderate/severe leptospirosis

A

Penicillin (1.5 million units IV or IM q6h) or Ceftriaxone (1 g/d IV) or
Cefotaxime (1 g IV q6h)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

chemoprophylaxis

A

Doxycycline (200 mg PO once a week) or Azithromycin (250 mg PO once or twice a week)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly