Fever of Unknown Origin Flashcards

1
Q

Define FUO

A
  1. Temperatures of >38.3°C (101°F) on several occassions
  2. Duration of fever of > 3 weeks
  3. Failure to reach diagnosis despite 1 week of inpatient investigation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Neutropenic FUO

A

Temperature of >38.3 °C (>101 °F) on several occasions in a patient whose neutrophil count < 500/uL or is expected to fall to that level in 1-2 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Classic FUO

A

3 outpatient visits or 3 days in the hospital without elucidation of a cause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Nosocomial FUO

A

Temp >38.3°C (>101 °F) on several occassions in hospitalized (acute care infection not manifested) or incubating on admission
MUST: 3 days investigation (2 days incubation of culture)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

HIV associated FUO

A

Temperature of >38.3 °C (>101 °F) on several occassions over a period of >4 weeks for outpatients or 3 days for hospitalized patients with HIV infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Infections

A

Leading diagnosable cause of FUO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Most frequent cause of FUO in the Elderly

A

o Multisystem disease (Giant cell arteritis leading)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Causes of FUO lasting > 6 months

A
None identified
MIsc
Factitious
Granulomatous hepatitis
Neoplasm
Still's disease
Infection
Collagen vascular disease
Familial mediterranean fever
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

ESR, leukocytosis, and anemia and is often accompanied by arthralgias, polyserositis (pleuritis, pericarditis), lymphadenopathy, splenomegaly, and rash.

A

still’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

examine the terminal ileum and cecum

A

o Upper GI contrast w/ small-bowel follow-through and colonoscopy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

systemic necrotizing vasculitis is suspected

A

arteriography

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

cause FUO nosocomial

A

50% - infectious cause
25% - noninfectious cause
20% - undiagnosed.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

empiric coverage of neutropenic FUO

A

vancomycin plus ceftazidime or
cefepime or,
carbapenem with or without an aminoglycoside

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Indication for empirical therapy with fluoroquinolone plus piperacillin

A

Vital sign instability

Neutropenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

ID pneumocystis infection

A

67-Ga scan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

most common cause of fever in HIV patient

A

infectious (>80%)

other causes: drug fever and lymphoma

17
Q

Therapeutic trial for TB

A

continued up to 6 weeks