Lehne Book: Chapter 3 - Drug Regulation, Development, Names, and Information

Question 1

What is the most reliant way to objectively assess drug therapies?

Answer 1

RCTs - Randomaly Controlled Trials

Question 2

What is the most reliant way to objectively assess drug therapies?

Answer 2

RCTs - Randomaly Controlled Trials

Question 3

What are three factors that make RCTs reliable?

Answer 3

Control groups, randomization, and blinding (blind tests)

Question 4

What are three factors that make RCTs reliable?

Answer 4

Control groups, randomization, and blinding (blind study)

Question 5

What is the main difference in preclinical versus clinical trials?

Answer 5

Animals are used in pre/Humans in clinical

Question 6

What are the goals of phase I in clinical trials?

Answer 6

1. evaluate drug metabolism
2. pharmacokinetics
3. Biologic effects

Question 7

Why is it hard to know what adverse effects will take place with longterm use of drugs?

Answer 7

Clinical trial periods are short.

Question 8

Drugs have three types of names. What are they?

Answer 8

1. chemical name (n-acetyl-para-aminophenol)
2. generic or non-proprietary name (acetaminophen)
3. Trade or proprietary name (brand name - tylenol)

Question 9

If there is a new med on the market that does the same thing as a drug that has been on the market for years, which do you prescribe?

Answer 9

The old. It has known side effects and effectiveness. The new one might have unknown risks.

Question 10

T or F: Brand name products can change active ingredients without changing the product name.

Answer 10

True. This may be dangerous for someone who may have problems with the new active ingredient. Inform patients about brand name medicines and this possibility.

Question 11

Why is labeling medication with the generic name (instead of the trade/brand name) a good idea?

Answer 11

If a patient has multiple doctors prescribing a med such as ibuprofen, the bottles will read the same and will be more easily recognized by the patient. This will decrease the chance of double dosing.

Question 12

T or F: Brand name products can change active ingredients without changing the product name.

Answer 12

True. This may be dangerous for someone who may have problems with the new active ingredient. Inform patients about OTC medicines and this possibility.

Question 13

Is there a diff in the drug of two brands of the same drug?

Answer 13

No. The difference may be absorption rate….