Lectures 7.3-8.1: Learning and Memory Flashcards

1
Q

Sensitisation

A

An enhanced response to many different stimuli after experiencing an intense or noxious one. For example, an animal responds more vigorously to a tone of lesser intensity once a painfully loud tone has been played.
A habituated response can be restored by sensitisation

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2
Q

Classical conditioning

A

A learning process in which an innate response to a potent stimulus comes to be elicited in response to a previously neutral stimulus; this is achieved by repeated pairings of the neutral stimulus with the potent stimulus.

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3
Q

Operant conditioning

A

The pairing of a behaviour with a stimulus. Through operant conditioning, an individual makes an association between a particular behaviour and a consequence through the use of positive or negative reinforcement

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4
Q

Implicit memories

A

Memories that are not consciously recalled

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5
Q

Duration of memory traces in working memory

A

Seconds to minutes

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6
Q

Working memory stores

A

newly acquired information and retrieved memories

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7
Q

Working memory depends on which area of the brain?

A

Prefrontal cortex and lateral intraparietal cortex

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8
Q

Subdivisions of working memory

A

Central executive - discrimination of different facial features, timing,
Phonological loop
Spatiotemporal sketchpad

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9
Q

Long term explicit memories are primarily stored in the

A

neocortex

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10
Q

Which region of the brain is required for the transfer of memories from working to long term?

A

Hippocampus

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11
Q

Explicit memory is subdivided into

A

somantic and episodic memory

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12
Q

Alzheimer’s dementia preferentially affect the

A

episodic memory

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13
Q

Adult neurogenesis occurs in the

A

dentate gyrus of the hippocampus

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14
Q

CaMKII is associated in rings of ___ subunits

A

10

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15
Q

CaMKII is a target for phosphorylation by

A

CaMKII

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16
Q

Phosphorylation causes CaMKII to be

A

constitutively active until dephosphorylated by a phosphatase

17
Q

An AP in post-synaptic neuron occurring before an EPSP activates

A

Ca2+dependent phosphatase leading to LTD

18
Q

NMDA-receptor mediated EPSP occurring before post-synaptic AP increase activates

A

CaMKII leading to LTP