Lecture 12.1-12.3: Pre-Frontal Cortex

Question 1

Epilepsy treatment

Answer 1

GABAergic agonists

Question 2

Antidepressants include

Answer 2

MAO inhibitors (MAO is the enzyme responsible for the destruction of all the monoamines - adrenaline, noradrenaline, dopamine, serotonin)
MA reuptake inhibitors (SSRI’s, NERI’s)
Lithium (may modulate phosphoinositol second messengers)

Question 3

Alcohol leads to a reduction in

Answer 3

brain weight, especially white matter, particularly in the cerebral cortex (frontal cortex, hypothalamus, cerebellum)

Question 4

Working memory is a function of which area of the brain?

Answer 4

Dorsolateral prefrontal cortex

Question 5

The last area of the brain to mature and obtain myelination is

Answer 5

Brodman’s area 46 – the top of the hierarchy in behavioural control.

Question 6

Function BA46

Answer 6

Ideates space and time and other abstractions

Question 7

Which BA are associated with tool recognition and function

Answer 7

BA 45 and 47