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CVS > Lecture36: Therapeutic Control Of Hypertension > Flashcards

Lecture36: Therapeutic Control Of Hypertension Flashcards

1
Q

What does Enalapril do?

A

Inhibits ACE from acting on angiotensin 1

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2
Q

What does Valsartan do?

A

Inhibits AT1R and decreases after load

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3
Q

What does spironolactone do?

A

Inhibit aldosterone

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4
Q

What are ACEIs and ARBs additional effects?

A

They prevent cardiac remodeling and slow renal disease progression + reflex tachycardia + HYPERCALEMIA AND DRY COUGH

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5
Q

What are ACEIs and ARBs effect on kidney?

A

They decrease glomerular pressure and proteinuria if GIVEN EARLY

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6
Q

What happens if ACEIs and ARBs are given late to kidney?

A

They cause blockage via decreased angiotensin 2

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7
Q

What does nebivolol do?

A

Increases NO synthesis via NO synthase stimulation

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8
Q

What is a non selective beta blocker?

A

Propranolol

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9
Q

What are the 2 selective beta 1 blockers?

A

Atenolol and metoprolol

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10
Q

What is the combined Alpha and Beta blocker?

A

Carvedilol

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11
Q

What do beta blockers decrease?

A

Cardiac output

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12
Q

Which part of the cardiac output do the selective B1 blockers decrease?

A

Heart rate

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13
Q

What do calcium channel blockers act on?

A

Voltage gated L-Type channels

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14
Q

Which calcium channel blocker acts on the myocardium?

A

Verapamil

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15
Q

Which calcium channel blocker acts on arteriolar smooth muscles?

A

Nifedipine

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16
Q

What is the intermediate between dihydropyridines and non-dihydropyridines?

A

Dilitazem

17
Q

What does the verapamil act on in the equation?

A

Cardiac output and thus, heart rate

18
Q

What does the nifedipine act on in the equation?

A

The afterload

19
Q

Which of nifedipine and verapamil can be combined with B-blockers?

A

Nifedipine

20
Q

What do Diuretics do?

A

They decrease salt and water reabsorption and decrease blood volume

21
Q

What is a diuretic additional effect?

A

Decreased calcium in VD

22
Q

What Extra is used in pregnancy?

A

A2 agonists

23
Q

J

A

CVS (17 decks)

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