Lecture3: Factors Affecting Erythropoiesis And Haemoglobin Formation

Question 1

What stimulates Erythropoietin hormone production?

Answer 1

Lack of O2

Question 2

Name 2 scenarios when Erythropoietin hormone is produced?

Answer 2

Hemorrhage or high altitude

Question 3

name the 3 other hormones

Answer 3

Thyroxine, androgens, and growth hormone

Question 4

Which vitamin influences growth of body tissues?

Answer 4

Vitamin C

Question 5

What does the liver secrete?

Answer 5

Vitamin B12 and folic acid

Question 6

What does the destruction of bone marrow cause?

Answer 6

Aplastic anemia, a deficiency in all blood cells

Question 7

Which 2 maturation factors are essential for maturation of RBCs’?

Answer 7

Vitamin B12 and folic acid

Question 8

Why are animal based proteins superior to plant based?

Answer 8

They contain EAAs

Question 9

What is the importance of iron relative to hemoglobin formation?

Answer 9

Forms the (heme) part

Question 10

What is the importance of copper and cobalt in hemoglobin synthesis?

Answer 10

They catalyze it, copper helps iron reabsorption, cobalt helps utilization of iron.

Question 11

How many heme fractions does one Hb molecule have?

Answer 11

4

Question 12

How many O2 can one heme fraction carry?

Answer 12

1

Question 13

Which part of the hemoglobin does O2 attach to?

Answer 13

The ferrous iron