Lecture Slides - Administration and Distribution (pg. 1, 8-16)

Question 1

____ is a chemical substance that dulls sensitivity to pain

Answer 1

narcotic

Question 2

___ ___ ___ = specific/specialized body tissue that is affected by the chemical

Answer 2

site of action

Question 3

sites of action are subjective to what?

Answer 3

the reason you are taking the drug

Question 4

Administration methods will determine:

• How much = ___, ____, ______
• How quickly = ___, _____ _____, _____ ____

Answer 4

routes, enzymes, metabolism

systems, chemical properties, blood-brain barrier

Question 5

Pros and cons of oral administration (3 of each)

Answer 5

Pros: convenient, least expensive, safest
Cons: slow absorption, delayed feedback, variability or absorption

Question 6

what is insufflation and sublingual?

Answer 6

insufflation = snorting
sublingual = under the tongue

Question 7

Pros and cons of absorption?

Answer 7

pro: rapid
cons: irritation, variable absorption

Question 8

pros and cons of inhalation?

Answer 8

pro: extremely fast absorption
cons: short lasting, respiratory irritation/damage, risk of brain damage (anoxia)

Question 9

Pros and cons of subcutaneous parenteral administration?

Answer 9

Pro: easiest
Cons: slowest of parenteral because it relies on absorption, can also cause skin irritation/deterioration

Question 10

Pros and cons of intramuscular parenteral drug administration?

Answer 10

Pros: requires less dexterity
Cons: risk of piercing a vein or getting an infection, also painful

Question 11

Pros and cons of intravenous parenteral drug administration?

Answer 11

Pros: fastest absorption, immediate effects, accurate dosages
Cons: cannot be recalled/anuled, abrupt imbalance can be lethal, infections disease transmission

Question 12

What is a potential factor of intravenous injection?

Answer 12

collapsed veins - begins to atrophy and withdraw, cuts off blood supply to the area