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MicroBio Immunity > Lecture Flow Chart > Flashcards

Lecture Flow Chart Flashcards

Cards over the chart made during Lecture

1
Q

The immune system must

A

recognise friend from foe

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2
Q

Who is foe

A

nonself

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3
Q

Who is friend

A

self

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4
Q

What does the immune system use as its eyes

A

Markers

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5
Q

Examples of Markers

A 
MHC I
MHC II
CD
Ig
TOLL-PAMP
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6
Q

“the name tag””

A

MHC I

MHC II

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7
Q

markers found on all nucleated cells

A

MHC I and MHC II

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8
Q

what does nucleated cells exclude

A

red blood cells

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9
Q

Where are CD markers found

A

T Cells

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10
Q

Where are Ig markers found

A

B Cells

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11
Q

Where are TOLL-PAMP markers found

A

white blood cells

APC and Macrophages

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12
Q

What does the immune system use as words

A

Cytokines

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13
Q

Examples of Cytokins

A

Bradykins
Interleukins
Histamines
prostagladin

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14
Q

Body Compartments

A

RES
ECF
Lymph sys
Vascular sys

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15
Q

Where is the lymph system most condensed

A

the extremites

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16
Q

Why is the lymphatic system more abundant in the hands and feet than the head

A

the extremities are more likely to incur injury

the lymphatic system functions as a drain off

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17
Q

importance of the Caridovasucular system

A

It is how everything gets around the body

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18
Q

RES?

A

Reticuloendothelial System

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19
Q

RES importance?

A

connect lymph and vascular system and the rest of the body

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20
Q

ECF

A

Extracellular Fluid

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21
Q

EFC importance?

A

allows the cells to move between the other 3 compartment

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22
Q

Lymphocytes EX

A

B Cells

T Cells

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23
Q

When do Lymphocytes participate in the immunity process

A

Specific

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24
Q

When do macrophages participate in the immunity process

A

Non-specific

Specific

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25
Q

Macrophages EX

A

phagocytes

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26
Q

When do dendrite participate in the immunity process

A

non-specific

specific

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27
Q

When do neutrophils appears in the immunity process

A

non-specific

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28
Q

When do basophils appears in the immunity process

A

non-specific

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29
Q

When do eosinophils appears in the immunity process

A

non-specific

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30
Q

What is the first line of defense called

A

Innate

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31
Q

What does innate mean

A

born with the immunity

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32
Q

Major types of innate immunity

A

Physical barrier
Chemical barrier
Genetic component

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33
Q 
Skin, hair, and nails
tears
mucus membrane
wax
voiding
Cilia
A

Physical barrier

34
Q

How does genes play a part in innate immunity

A

the DNA expression is what allows for the body to have them

35
Q 
Lysozyme
salt
fatty acids
Stomach Acid
amylase
A

chemical barrier

36
Q

what is the second line of defense called

A

Non-specific

37
Q

why is it non-specific

A

The mechanisms employeed do not target a specific antigen

38
Q

non-specific mechanisms

A

fever
inflammation
phagocytosis
antimicrobial proteins

39
Q

Which markers recognize antigens

A

CD

Ig

40
Q

which marker marks pathogens

A

TOLL-PAMP

41
Q

What does fever do to the body

A

increases temp
increase WBC
Decreases pathogen metabolism
Decrease available Fe, sugar

42
Q

Antimicrobial proteins

A

siderphores
complement
defensins
interferons

43
Q

What are the outcomes of complement

A

Lysis
inflammation
opsonization

44
Q

What is the process of inflammation

A

injury
vascular reaction
edema
resolution

45
Q

What is the process of phagocytosis

A 
Chemotaxis
adhesion
engulfment
phagolysosome
destruction 
elimination
46
Q

what kind of cells release interferons

A

infected self

47
Q

What kind of reaction is complement

A

it is a cascade reaction

48
Q

what is a cascade reaction

A

when one event directly causes subsequent reactions to occur

49
Q

what happens when the 2nd stage was overwhelmed

A

the 3rd, specific stage sets in

50
Q

antibodies

A 
neutralization
agglutinate
antitoxins
opsonization
Trigger complement
51
Q

Specific process

A

maturation
presentation
activation
response

52
Q

goal of Vaccination

A

prodution of memory cells

53
Q

types of immunity

A

active natural
active artifical
passive natural
passive artifical

54
Q

active natural

A

sickness

55
Q

active artificial

A

Vaccination

56
Q

passive natural

A

breast feeding; from mother

57
Q

passive artificial

A

antibody therapy

58
Q

Histamine cytokines causes

A

inflammation

59
Q

Prostaglandin cytokines causes

A

wheezing

60
Q

Bradykinin cytokines causes

A

increased mucous production

61
Q

Leukotrienes cytokines triggers

A

mucous

62
Q

where do the T Cells mature

A

The thymus

63
Q

where do B Cells mature in the blood

A

the bone marrow

64
Q

What happens in the presentation stage

A

APC shows T Cell antigens and T Cell shows B Cells

65
Q

What happens during activation

A

Proloferation and differentiation

66
Q

what do the lymphocytes differentiate into

A

B Cells make plasma and memory

T Cells make Helper T and memory

67
Q

How do the lymphocytes respond

A

B Cells make antibodies

T Cells further differentiate

68
Q

What are antibodies functions

A 
complement
coat
neutralize
agglutinate
anti-toxin
opsonization
69
Q

hypersensitivies II

A

blood incompatibility

70
Q

what happens when blood is incompatable

A

Self blood can call for antibodies to agglutinate nonself

71
Q

why can mothers blood attack fetus blood

A

bc of Rh factor incompatibility

72
Q

Hypersensitivies III

A

antibody complex

73
Q

process of type III

A

Antibodies clump to attract chompenaters but sometimes they enter the capillary and trigger complement

74
Q

Hypersensitivities IV

A

coordinates attack against the wrong cells

transplant rejection

75
Q

graph v Host

A

host accepts tissue and the tissue has its own lymphocytes/immune system and mounts an attack on host

76
Q

Host v Graft

A

host recognizes the graft as foreign and T Cells attack it

77
Q

Secondary Immundeficency

A

organic disease, noninfection
Chemotherapy
Radiation
infection

78
Q

Immune Cells

A 
dendrites
Basophils
eosinophils
neutrophils
lymphocytes
macrophages
mast cells
79
Q

Chompenators

A

Neutrophils
macrophages
dendrites

80
Q

APC

A

B cells
dendrites
macrophages

81
Q

what happens in type IV conatact dermititis

A

picks up allogen instead of antigens

MicroBio Immunity (5 decks)

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