Lecture 9 Haematology II White Blood Cells Flashcards
State another name of a white blood cells
Leukocytes. Leukocytes refers to all the different types of WBCs.
Make sure you can identify the different types of WBCs from photographs
Check one-note for graphs after active recall.
What is the buffy coat
Contains mostly leukocytes (WBCs) and platelets
Which cells are contained in the buffy coat
Mainly platelets, leukocytes ( including neutrophils, lymphocytes, monocytes, basophils and Eosinphils)
List the functions of leukocytes
Defence of pathogens
Toxin and waste removal
Removal of damaged cells
Acts mainly outside the tissues
List the key features common of all white blood cells
All can migrate out of the bloodstream.
all capable of amoeboid movement.
all attracted to chemical stimuli
How are leukocytes (wbc’s) charactarized?
There are 2 categories of leukocytes.
1) Granulocytes
2) Agranulocytes
What does extravasation mean
This is the ability of white blood cells to migrate out of the blood stream
Which feature of Leukocytes is used as an indicator of disease
The number of leukocytes present in the blood.
What is the ratio of RBCs to platelets and white blood cells
700 RBC’s :40 platelets : 1 white blood cell.
Name the most common type of leukocyte
Neutrophils are the most common.
State the normal white blood cell count
Approx 4-11 x 10^9 white blood cells per litre of blood.
Describe the strucure of neutrophils
- most common
- 9-15 um in diameter
- distinctive nucleus with 2-5 lobes
- granular cytoplasm
Describe the functions of neutrophils
- First line of defense against bacterial infection.
- phagocytic
- mobile
- circulate in the blood for approx 10 hrs.
- major constituent of pus
Which of the white blood cells are phagocytic
Neutrophils, Eosinophils and Monocytes