Lecture 9 & 10: Growth, Bones & Aging Flashcards
1
Q
What are the 2 types of growth spurts?
A
Postnatal & pubertal
2
Q
Factors that influence growth
A
- Hormone levels (primarily GH)
- Genetics
- Diet
- Stress
3
Q
What is GH secreted by?
A
Anterior pituitary gland
4
Q
What is GH stimulated by?
A
GH releasing hormone (GHRH)
5
Q
What is GH inhibited by?
A
GH inhibiting hormone (GHIH)
6
Q
Does growth hormone what metabolic and growth affects?
A
YES BOTH
7
Q
Is GH release higher during the day or at night?
A
NIGHT
8
Q
How does GHRH work?
A
- GHRH acts on AP (cells that release the hormone into the bloodstream)
- Metabolic effects
- Acts on liver to release IGS
- Stimulates growth of bone & soft tissue
- Increase in IGF stimulates release of GHIH
9
Q
What are the metabolic effects of GH?
A
- Acts on adipose tissue, skeletal muscle and liver to CONSERVE GLUCOSE FOR THE BRAIN
- Metabolises lipids
- Increases BG
10
Q
How does GH promote growth?
A
- Increases the number & size of cells
- Increases bone thickness & length
11
Q
Where do long bones grow at?
A
Epiphyseal plate (from cartilage)
12
Q
When does the epiphyseal plate close?
A
During late adolescence (thus don’t grow anymore)
