Lecture 8: Vision II Flashcards
List in order the cellular layers of the retina.
- Photoreceptors
- Horizontal cells
- Bipolar cells
- Amacrine cells
- Ganglion cells
Which cells make up the photoreceptor retinal layer?
- rods
- cones
What does photoreceptors do?
Transmit signals to outer plexiform layer.
** plexiform layer = layer of synaptic connections **
What type of cells does the photoreceptors synapse with?
- Bipolar Cells
- Horizontal Cells
Where do horizontal cells transmit signals to?
- Transmit signals from rods and cones to bipolar cells
- Transmit signals to outer plexiform layer
Is the output of horizontal cells inhibitory or excitatory?
Output is always inhibitory (lateral inhibition).
Where do bipolar cells transmit signals to?
- Transmit signals from rods, cones, and horizontal cells.
- Transmit signals to inner plexiform layer.
Which cells do bipolar cells synapse with?
- Amacrine cells
- Ganglion cells
What signals do amacrine cells transmit?
- Transmit signals:
- directly from bipolar to ganglion cells
- within inner plexiform layer from axons of bipolar cells to dendrites of ganglion cells or to other amacrine cells
Which type of cells in the retinal layers transmits signals from the retina to the brain?
Ganglion Cells !!!!!
What do the axons of ganglion cells make up?
Optic Nerves
What are the only retinal cells that transmit action potentials?
Ganglion Cells
Except for ganglion cells, what type of conduction does the other cell types use?
Electrotonic conduction which allows graded conduction of signal strength.
What do interpexiform cells do?
transmit from inner plexiform layer to outer plexiform layer (retrograde)
Are interplexiform cells involved in lateral inhibition?
Yes - fine tune original image that is picked up by the rod and cone cells.
What are the four neurons that compose pure rod vision?
- rods
- bipolar cells
- amacrine cells
- ganglion cells
In the foveal region, what are the three neurons that compose the direct pathway?
- cones
- bipolar cells
- ganglion cells
Which neurotransmitter goes from the rod and cones to bipolar cells?
Glutamate
Which neurotransmitters are released from amacrine cells?
- GABA
- glycine
- dopamine
- acetylcholine
- indolamine
**they are ALL INHIBITORY**
What are the functions of amacrine cells?
- About 30 kinds:
- one type is part of direct pathway for rod conduction
- one type responds strongly to onset of continuing visual signal but fades rapidly
- some types respond strongly at the offset of visual signals, but the respone fades rapidly
- some respond when a light is turned on or off
- one type responds to movement of a spot across the retina in a specific direction
- THEREFORE, MOST AMACRINE CELLS ARE INTERNEURONS THAT HELP ANALYZE VISUAL SIGNALS BEFORE THEY LEAVE THE RETINA!
What are the 3 types of ganglion cells?
W, X, and Y
How many rods and cones converge on each ganglion cell and the optic nerve fiber from the ganglion cell?
Average 60 rods and 2 cones.
What happens to the number of rods and cone that converge on each ganglion cell as you approach the fovea?
Fewer rods and cones converge on each optic fiber and rods and cones become more slender:
- increased visual acuity in central retina
- in central fovea there are only slender cones ( about 35,000) and NO rods.
Is the peripheral retina more sensitive to weak light?
Yes - thus night vision is better out of the corner of your eye.
- As many as 200 rod converge on a single optic fiber in the more peripheral regions of the retina.
What percentae of ganglion cells are made up of W type and what is its function?
- 40%
- Small
- Transmit signals 8 m/sec
- Receive most of their excitation from rods transmitted by way of small bipolar cells ad amacrine cells
- They have broad fields in the peripheral retina because their dendrites spread widely in the inner plexiform layer.
How do W ganglion cells receive most of their excitation?
From rods transmitted by way of smal bipolar cells and amacrine cells.
Why do W ganglion cells have broad fields in the peripheral retina?
Because their dendrites spread widely in the inner plexiform layer.
What percentage of ganglion cells are made up of X-type and what are their functions?
- 55%
- Medium diameter
- Transmit signals 14 m/sec
- They have small fields
- signals represent discrete retinal locations
- Every X ganglion cell receives input from at least one cone cell; therefore, probably responsible for ALL color vision.
Which type of ganglion cell is probably responsible for ALL color vision?
X ganglion cells