Lecture 8: Stereoisomerism Flashcards
Isomers that are not interconverted by sigma bond rotation.
Configurational Isomers
Have different spatial arrangements of the same compound.
Conformers
A molecule that is not superimposable on its mirror image.
Chiral
A molecule that is superimposable on its mirror image.
Achiral
An imaginary plane passing through an object, dividing it such that one half is a reflection of the other half.
Plane of Symmetry
A carbon atom bonded to four different groups.
Stereocenter
Compounds that are non-superimposible mirror images.
Enantiomers
Molecules with two or more chiral centers, and contain stereoisomers that are not mirror images.
Diasteromers
An achiral molecule that contains at least one stereocenter and a plane of symmetry.
Meso Compound
The two possible configurations of spatial arrangements of stereoisomers.
Configurations
Typically, the letter ___ is assigned to stereoisomers arranged clockwise.
R
Typically, the letter ___ is assigned to stereoisomers arranged counterclockwise.
S
When assigning priority in stereoisomers, 1 is assigned to the _____ group.
Heaviest
When assigning priority in stereoisomers, 4 is assigned to the _____ group.
Lightest
Each group bonded to the chiral carbon is ranked based on _____
Atomic number
If the lowest substituent is a _____, assign all groups according to the rule but switch the assignment of R or S to the opposite.
Wedge Bond
A compound is considered _____ if it interacts in such a way as to rotate the plane polarized light.
Optically Active
Instrument used to determine the optical activity of a compound.
Polarimeter
Achiral molecules are termed “optically _____”
Inactive
Chiral molecules are termed “optically _____.”
Active
A standardized measurement to account for sample concentration, wavelength of light, and length of sample tube.
Specific Rotation
An additional way of representing 3D information in a 2D drawing.
Fisher Projections
