lecture 8: biological changes with aging Flashcards

1
Q

describe the changes in height

A
  • between age 20 and 80 average loss in height is 1-4 inches
  • flattening of arch in feet
  • increased spinal curvature
  • atrophy of back muscles
  • compaction of vertebrae
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2
Q

Describe the changes in weight

A
  • increases in percentage of body fat (pharmacology changes)
  • decrease in size of arm and legs
  • increased in size of truck (redistribution)
  • thought is as you age you may grow thinner (variable)
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3
Q

aging of bones

A
  • loss of calcium due to decrease absorption in upper GI tract
  • hormone changes that affect bone structure
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4
Q

Nails

A
  • slower growth
  • dull appearance
  • brittle and flake
  • color changes from translucent to yellow/opaque
  • tips easily fragments
  • longitudinal ridges
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5
Q

Hair

A
  • loss of facial and body hair
  • hair pigment decreases (decreased melanin production)
  • decreased production - failure to replace hair follicles
  • individual hairs coarser
  • -> female - chin
  • -> Males - brow, ears, nose
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6
Q

changes with skin

A
  • THINNING OF EPIDERMIS
  • loss of elasticity
  • loss of subcutaneous adipose tissue
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7
Q

Consequence of skin changes

A
  • impaired temperature regulation***
  • dry (xerosis) flaky skin
  • skin folds and wrinkles**
  • aging pallor
  • coarser features - bony appearance
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8
Q

clinical applications

A
  • role of photo aging (solar degerenatio
  • Pruritus (itching) 2/3 of older adults
  • bed sores
  • increase in skin cancer
  • actinic keratosis
  • telangiectasis
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9
Q

eyes and vision

A
  • eyelids baggy and wrinkled
  • eyes deeper in sockets
  • quality of tears decrease
  • iris fades
  • depth perception is lost
  • floaters show up
  • pupils smaller, let in less light
  • lens enlarges = less transparent = clouded
  • Accommodation decreases
  • impaired color vision (green and blues)
  • cones degenerate
  • central vision occlusion
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10
Q

ears

A
  • irreversible sensorineural loss with age

- normal speach changes

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11
Q

respiratory

A
  • lungs become more rigid
  • pulmonary function decreaes
  • number of size of alveoli decreases
  • vital capacity declines
  • reduction in respiratory fluid
  • bondy changes in chest cavity
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12
Q

heart

A
  • can be reduced by up to 70% in 70 yo
  • heart valves become sclerotic
  • heart muscle more irritable (more arrhythmia’s due to hypoxia)
  • arteries more rigid
  • veins dilate
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13
Q

Female reproductive

A
  • declines in estrogen and progesterone
  • vagina atrophies, shorter, drier
  • uterus becomes smaller
  • breast tissue lose elasticity
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14
Q

males

A
  • reduced testosterone
  • testes atrophhy and soften
  • decrease in sperm production
  • seminal fluid decreases and more viscous
  • erections take more time
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15
Q

immune system

A
  • overal decline in function
  • trouble differentiating between self and non-self
  • decreased antibody response
  • vitamin B12 absorption decreases
  • decreased hemoglobin and hematocrit
  • restorative process takes longer
  • exerise improves the immune system**
  • flu shots, pneumonia shots
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16
Q

Nervous system

A
  • bran is much mroe plastic then traditionally thought
  • bran can lose up to 10% in weight
  • cerebral blood flow - by age 70, up to 20% decrease
  • neurotransmitter changes
    –> decrease in dopamine (parkinsons)
    –> acetylcholine decrease (dementias)
    –> GABA - slowing of sensroy info
    -
17
Q

aging effects of sensory- motor function

A
  • impaired balance - posture
  • slow widened gait
  • jerky, clumsy coordination
  • resting tremor (parkinsonism)
18
Q

reversible causes of dementias

A
  • drugs
  • emotional disorders
  • metabolic or endocrine disorders
  • Eye and Ear dysfunction
  • Nutrintional deficiencies
  • tumors and trauma
  • infections
  • arteriosclerosis
  • *DEMENTIA**
19
Q

Leading causes of death

A
  • heart disease
  • cancer
  • chronic lower respiratory disease
  • strokes
  • alzheimer’s disease
  • diabetes mellitus
  • influenza and pneumonia