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Pharmacology Drugs :) > Lecture 8 > Flashcards

Lecture 8 Flashcards

1
Q

What are examples of rapid-acting insulin?

A

Humalog (lispro) NovoLog

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2
Q

What are examples of short-acting insulin?

A

Humulin R Novolin R

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3
Q

What are examples of intermediate-acting insulin?

A

Humulin N,L Novolin N,L

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4
Q

What are examples of long-acting insulin?

A

Ultralente Lantus (glargine)

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5
Q

Examples of Beta-call dysfunction

A

Sulfonylureas Glinides DPP-4 inhibitors

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6
Q

What are examples of insulin resistance

A

TZDs (Glitazones) Biguanides

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7
Q

Examples of glucose absorption

A

Alpha-glucosidase inhibitors Biguanides

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8
Q

Examples of hepatic glucose overproduction

A

Biguanides TZDs (Glitazones) DPP-4 inhibitors

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9
Q

What is the first generation sulphonylureas

A

Tolbutamide Chlorpropamide

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10
Q

What is second generation sulphonylureas?

A

Glibenclamide

Glipizide

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11
Q

What are examples of Thiazolidinesdiones?

A

Troglitazone Pioglotazone

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12
Q

What does PPAR alpha do in the liver?

A

Increase fat oxidation Increase fasting response

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13
Q

What does PPAR alpha do in the muscles?

A

Increase fat oxidation

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14
Q

What does PPAR Gamma do in the muscle?

A

Increase insulin action

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15
Q

What does PPAR Gamma do in the adipose tissue?

A

Increase adipocyte differentiation and survival Increase fat uptake and storage

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16
Q

What does PPAR Gamma do in the blood?

A

Decrease lipid concentration

17
Q

What does PPAR delta do in the muscle?

A

Increase fat oxidation Increase energy expenditure

18
Q

What does PPAR delta do in the adipocyte tissue?

A

Increase fat oxidation Increase energy expenditure

Pharmacology Drugs :) (17 decks)

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