Lecture 22 Flashcards

1
Q

Drugs that mimic Parkinson like symptom

A
Neurotoxin 
E.g. MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine)
Dopamine antagonist 
E.g. chlorpromazine 
Depletion 
Reserpine blockage of vMAT
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2
Q

What is a selective inhibitor of MAO8

A

Selegiline

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3
Q

D2 antagonist

A

Prochlorperazine

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4
Q

Direct dopamine agonist

A

Bromocriptine

Apomorphine

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5
Q

Release of dopamine

A

Amantadine

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6
Q

Block cholingeric effects

A

Benztropine

Benzhexol

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7
Q

Peripherally-acting DOPA decarboxylase inhibitor

A

Carbidopa

Benserazide

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8
Q

Dopamine antagonist

A

Domperidone

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9
Q

COMT inhibitor

A

Entacopone

Tolcapone

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10
Q

Dopamine agonist

A

Bromocriptine and pergolide
Pramipexole and ropinirole
Apomorphine

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