Lecture 4 Flashcards

1
Q

CYP1A2

A

Caffeine, paracetamol, tacrine, theophylline

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2
Q

CYP2B6

A

Cyclophosphamide, methadone

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3
Q

CYP2C8

A

Paclitaxel, repaglinide

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4
Q

CYP2C18

A

Omeprazole, phenytoin

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5
Q

CYP2C9

A

Ibuprofen, tolbutamide, warfarin

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6
Q

CYP2D6

A

Codeine, debrisoquine, S-metoprolol

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7
Q

CYP2E1

A

Alcohol, paracetamol

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8
Q

Phenobarbital

A

Acidic, alkalinising the urine increases the clearance about 5-fold

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