Lecture 3 Flashcards
Heparin
Anticoagulant Confined to plasma compartment when given intravenously
Diazepam
Anti anxiety, muscle relaxant, sleeping aid Distributes amongst all body fluids
Digoxin
Used to treat some heart problems a large proportion is taken out of solution by non-specific Binding
What is the Heparin volume of distribution?
3.5L
What is Diazepam volume of distribution ?
41.4L
What is Digoxin volume of distribution?
350L
Aspirin
Weak acid Absorption favoured in the stomach where it is unchanged and not in plasma or ruins where it is highly charged
Morphine
Weak base that is highly charged in stomach, quite charged in plasma and half charged in urine
Pethidine
Painkiller that is often used in aesthetics