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pharmacology > lecture 8 > Flashcards

lecture 8 Flashcards

1
Q

Normal values of cholesterol

A

<200

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2
Q

Normal values of Triglycerides

A

<150

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3
Q

Normal values of LDL

A

<100

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4
Q

Normal values of HDL

A

> 60

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5
Q

How long does it take for effects to be seen

A

6 weeks

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6
Q

what do statins interfere with

A

warfarin = high INR, longer bleeding time

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7
Q

rosuvastatin

A

increased serum levels in asians so give lower dose than regular

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8
Q

Main SE for statins

A

headaches, myopathy (muscle aches), and rhabdomyolysis

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9
Q

what vitamin should you take to prevent myopathy

A

vitamin d

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10
Q

what time should you take statins

A

In the PM because you create more cholesterol at night and it lowers levels and burns off the cholesterol instead of food

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11
Q

what does BABA reduce

A

Pruritus by detoxifying in the liver

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12
Q

3 BABAs

A

Cholestyramine
Colestipol
Colesevelam

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13
Q

BABA Bile acid suppressants

A

decreased vitamin K , headaches , constipation

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14
Q

BABA SE PREVENTION

A

Take fiber and fluidsw

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15
Q

what time should you take BABA if taken with other drugs

A

1 hour before or 4-6 after

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16
Q

what is niacin

A

a B vitamin that’s made and used by your body to turn food into energy

17
Q

NIACIN SE

A

Niacin SE
Insulin resistant ,myopathy , orthostatic hypotension, flushing, pruritus ,Gerd

18
Q

how do you reduce flushing and pruritus

A

take aspirin or ibuprofen 30 mins before or take with food

19
Q

Nursing consideration for niacin

A

find baseline Blood glucose

20
Q

what is Fibric acid more effective in

A

Most effective agent in reducing triglycerides

21
Q

what is the MOA of fibric acid

A

works by reduce the fatty acid the liver releases therefore reducing the amount of triglyceride synthesis

22
Q

fibric acid medications

A

Gemfibrozil
Fenofibrate [tricor]

23
Q

SE for fibric acid

A

Diarrhea , headaches , increased risk of gallstones

24
Q

what does fibric acid interact with

A

warfarin

25
Q

Medication for cholesterol absorption inhibitors

A

Ezetimibe

26
Q

what nutrients in cholesterol absorption inhibitors prevent heart dysrhythmias

A

omega 3 fatty acid

27
Q

THE 3 Immunostimulants [promote immune system and fight cancers ]

A

-interleukins , Promote more defense to area (SE flu like symptom and edemas due to capillary)
- interferon (prevent replication of cells )( SE fatigue)
-MAB[monoclonal antibodies ] (take out antibodies and multiply in body )

28
Q

Immunosuppressants

A

Used for rheumatoid arthritis you can tell difference bc pain is developed on both sides of the body and osteoarthritis is only in specific areas

29
Q

medication for immunosuppressants

A

HUMIRA

30
Q

how long is conventional medication

A

more than 2 weeks

31
Q

how long is biological medication

A

less than 2 weeks (humira and leucovorin )

pharmacology (11 decks)

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