lecture 8 Flashcards
Normal values of cholesterol
<200
Normal values of Triglycerides
<150
Normal values of LDL
<100
Normal values of HDL
> 60
How long does it take for effects to be seen
6 weeks
what do statins interfere with
warfarin = high INR, longer bleeding time
rosuvastatin
increased serum levels in asians so give lower dose than regular
Main SE for statins
headaches, myopathy (muscle aches), and rhabdomyolysis
what vitamin should you take to prevent myopathy
vitamin d
what time should you take statins
In the PM because you create more cholesterol at night and it lowers levels and burns off the cholesterol instead of food
what does BABA reduce
Pruritus by detoxifying in the liver
3 BABAs
Cholestyramine
Colestipol
Colesevelam
BABA Bile acid suppressants
decreased vitamin K , headaches , constipation
BABA SE PREVENTION
Take fiber and fluidsw
what time should you take BABA if taken with other drugs
1 hour before or 4-6 after
what is niacin
a B vitamin that’s made and used by your body to turn food into energy
NIACIN SE
Niacin SE
Insulin resistant ,myopathy , orthostatic hypotension, flushing, pruritus ,Gerd
how do you reduce flushing and pruritus
take aspirin or ibuprofen 30 mins before or take with food
Nursing consideration for niacin
find baseline Blood glucose
what is Fibric acid more effective in
Most effective agent in reducing triglycerides
what is the MOA of fibric acid
works by reduce the fatty acid the liver releases therefore reducing the amount of triglyceride synthesis
fibric acid medications
Gemfibrozil
Fenofibrate [tricor]
SE for fibric acid
Diarrhea , headaches , increased risk of gallstones
what does fibric acid interact with
warfarin
Medication for cholesterol absorption inhibitors
Ezetimibe
what nutrients in cholesterol absorption inhibitors prevent heart dysrhythmias
omega 3 fatty acid
THE 3 Immunostimulants [promote immune system and fight cancers ]
-interleukins , Promote more defense to area (SE flu like symptom and edemas due to capillary)
- interferon (prevent replication of cells )( SE fatigue)
-MAB[monoclonal antibodies ] (take out antibodies and multiply in body )
Immunosuppressants
Used for rheumatoid arthritis you can tell difference bc pain is developed on both sides of the body and osteoarthritis is only in specific areas
medication for immunosuppressants
HUMIRA
how long is conventional medication
more than 2 weeks
how long is biological medication
less than 2 weeks (humira and leucovorin )
