Lecture 1

Question 1

chemical name

Answer 1

describes drugs chemical composition & molecular structure

Question 2

generic name

Answer 2

name given by the US ( not capitalized )

Question 3

trade name

Answer 3

registered trademark (capitalized)

Question 4

which is more effective generic or trade

Answer 4

trade is more effective than generic because it goes through more trials

Question 5

pharmacokinetics

Answer 5

how your body affects the drug

Question 6

pharmacodynamics

Answer 6

how the drug affects the body

Question 7

what are the 4 stages of pharmacokinetics

Answer 7

1. absorption
2. distribution
3. metabolism
4. excretion

Question 8

what is absorption ?

Answer 8

the movement of the drug from site of administration into bloodstream, depends on route

Question 9

what is distribution ?

Answer 9

drug transport by bloodstream to site of action, depends on circulation

Question 10

what is metabolism ?

Answer 10

drug biotransformation, depends on enzymes

Question 11

what is excretion ?

Answer 11

the elimination of metabolites and some of active drug depending on GI tract and kidneys (kidneys eliminate medication )

Question 12

where is medication activated?

Answer 12

in the liver

Question 13

two factors that alter the effectiveness of a drug

Answer 13

grapefruit and smoking

Question 14

what is the first pass effect

Answer 14

intestinal & hepatic degration or a heration of drug taken by mouth removing active substance from blood before it enters the systemic circulation

Question 15

what is biotransformation

Answer 15

medication activated by liver

Question 16

bioavailability

Answer 16

availability of the drug (IV bioavailability is 100%)

Question 17

prodrug

Answer 17

inactive drug until activated by the liver

Question 18

bioequivalent

Answer 18

2 different drugs

Question 19

what factors affect absorption

Answer 19

the area, time, circulation, solubility, bioavailability, and route

Question 20

what is enteral medication ?

Answer 20

suppositories and by mouth

Question 21

what is parenteral medication ?

Answer 21

IV

Question 22

chelation

Answer 22

metal ion that makes medication harder to absorb

Question 23

half life of a drug

Answer 23

amount of time required for 50% of the drug to be eliminated from the body

Question 24

therapeutic range

Answer 24

concentration of drug to be in effect

Question 25

steady ste

Answer 25

intake and elimination in equilibrium

Question 26

peak level

Answer 26

highest blood level of a drug

Question 27

trough level

Answer 27

lowest blood level of a drug

Question 28

toxicity

Answer 28

peak blood level when drug is too high

Question 29

therapeutic drug monitoring

Answer 29

depends on half life time

Question 30

what are side effects

Answer 30

effects that are expected

Question 31

what are adverse effects

Answer 31

effects that need to be reported bc they are unexpected

Question 32

MOA

Answer 32

mechanism of action

Question 33

NC

Answer 33

nursing consideration

Question 34

pharmacotherapeutics

Answer 34

drugs that prevent and treat diseases

Question 35

what is contraindication

Answer 35

withholding medication

Question 36

palliative

Answer 36

not curative, they just calm down the signs and symptoms ( it treats the signs and symptoms not the disease)

Question 37

prophylactic medication

Answer 37

prevents the spread of disease

Question 38

tolerance

Answer 38

decreasing response to repeating drug doses

Question 39

dependance

Answer 39

physiologic or psychological need for a drug

Question 40

physical dependence

Answer 40

physiologic need for a drug to avoid physical withdrawal symptoms

Question 41

phychological dependance

Answer 41

obsessive desire for the effects of a drug