lecture 7 Flashcards
_______drug for urine relaxant & asthma
Salbutamol
Clonidine for ?
____ _/agonist
HTN
a2 agonist
lofexidine is ___ _/agonist
for?
a2 agonist
treatment of opioid withdrawal.
Dexmedetomidine is ___ _/agonist
for?
a2 agonist
short-term sedation in an ICU
Tizanidine is ___ _/agonist
for?
alpha 2 agonist
central muscle relaxant
Brimonidine is ___ _/agonist
for?
a2 agonist
reduces production of aqueous humor and increases the flow of
aqueous humor out of the eye, resulting in a decrease in pressure
thus indicated in glaucoma.
Captagon is made of الكبت
fenethylline and amphetamine
captagon causes ?
CVS disorders like ventricular fibrillation and cerebral hemorrhage.
Amphetamine is \: direct/indirect symp/para \: actions \:indications \:S.E :
1-indirect symp
2- 1- release NE 2- produce stimulant effect on mood
and alertness and increases mental activity 3- Decreases appetite 4- produce euphoria
(happiness)
3- narcolepsy /ADHD
4- may lead to addiction and abuse (dependence).
Cocaine \: direct/indirect symp/para \: actions \:indications \:S.E
1-indirect symp
2-It Inhibits reuptake the NE - stimulation of the receptors (cause vasoconstriction) so it may lead to sudden rise in BP and overdose causing cerebral hemorrhage.
3-used in some surgeries, Oronasal specially
4 -addiction and abuse
nebivolol can causes?
vasodilation by releasing NO
Inderal drug was made by ____
the chemical name is
which is ____ _/ agonist
for ?
sir James
propranolol
`adrenergic antagonis beta blocker gen 1
~hypertension, ischemic heart disease (first choice of stable angina) and certain arrhythmias (ventricular) because it has the ability to decrease heart rate
for esophageal varices we use
propranolol+ nadolol
for Infantile hemangiomas ?
propranolol
The side effect of Beta- blockers:{5}
1- Bronchoconstriction.
2- Hypotension, Bradycardia.
3- Cold extremities because they decrease blood flow to the
extremities by decreasing outflow of the heart.
4- Nightmares, vivid dreams.
5- Masking symptoms of hypoglycemia. (All symptoms except
sweating).
6- Prolongation of insulin-induced hypoglycemia.
7- Fatigue (DUE TO reduce CO).
- Drugs that lead to hypoglycemia are
insulin or oral sulfonylurea.
How the B-blockers masking symptoms of hypoglycemia?
- Beta blocker will lead to hypoglycemia (decrease glucose level).
- Diabetes patient with hypoglycemia will feel this by sympathetic symptoms (tachycardia,
tremor, sweating, palpitation), beta blocker will mask all hypoglycemia symptoms except
sweating (because sweat glands have muscarinic receptor).
cardioselective beta blocker is ?
Atenolol
_______ used for Stable angina / diabetic hypertensive patients who are receiving insulin or oral antidiabetic agent
Atenolol
Timolol is
selective/non ______ agonist/antagonist
used for
Nonselective, blocks B1and B2
local use in the eye because it lacks local anesthetic properties.
open-angle glaucoma.
- It reduces aqueous humor production through blockage of β receptors on the ciliary epithelium
pilocarpine is similar to
Timolol
Adverse effect of beta blocker:
Topical timolol may interact with orally administered verapamil and increase the risk of heart block.
