lecture 7

Question 1

_______drug for urine relaxant & asthma

Answer 1

Salbutamol

Question 2

Clonidine for ?

____ _/agonist

Answer 2

HTN

a2 agonist

Question 3

lofexidine is ___ _/agonist

for?

Answer 3

a2 agonist

treatment of opioid withdrawal.

Question 4

Dexmedetomidine is ___ _/agonist

for?

Answer 4

a2 agonist

short-term sedation in an ICU

Question 5

Tizanidine is ___ _/agonist

for?

Answer 5

alpha 2 agonist

central muscle relaxant

Question 6

Brimonidine is ___ _/agonist

for?

Answer 6

a2 agonist

reduces production of aqueous humor and increases the flow of
aqueous humor out of the eye, resulting in a decrease in pressure
thus indicated in glaucoma.

Question 7

Captagon is made of الكبت

Answer 7

fenethylline and amphetamine

Question 8

captagon causes ?

Answer 8

CVS disorders like ventricular fibrillation and cerebral hemorrhage.

Question 9

Amphetamine is
\: direct/indirect symp/para
\: actions
\:indications
\:S.E :

Answer 9

1-indirect symp

2- 1- release NE 2- produce stimulant effect on mood
and alertness and increases mental activity 3- Decreases appetite 4- produce euphoria
(happiness)

3- narcolepsy /ADHD

4- may lead to addiction and abuse (dependence).

Question 10

Cocaine 
\: direct/indirect symp/para
\: actions
\:indications
\:S.E

Answer 10

1-indirect symp
2-It Inhibits reuptake the NE - stimulation of the receptors (cause vasoconstriction) so it may lead to sudden rise in BP and overdose causing cerebral hemorrhage.
3-used in some surgeries, Oronasal specially
4 -addiction and abuse

Question 11

nebivolol can causes?

Answer 11

vasodilation by releasing NO

Question 12

Inderal drug was made by ____
the chemical name is
which is ____ _/ agonist
for ?

Answer 12

sir James
propranolol
`adrenergic antagonis beta blocker gen 1
~hypertension, ischemic heart disease (first choice of stable angina) and certain arrhythmias (ventricular) because it has the ability to decrease heart rate

Question 13

for esophageal varices we use

Answer 13

propranolol+ nadolol

Question 14

for Infantile hemangiomas ?

Answer 14

propranolol

Question 15

The side effect of Beta- blockers:{5}

Answer 15

1- Bronchoconstriction.
2- Hypotension, Bradycardia.
3- Cold extremities because they decrease blood flow to the
extremities by decreasing outflow of the heart.
4- Nightmares, vivid dreams.
5- Masking symptoms of hypoglycemia. (All symptoms except
sweating).
6- Prolongation of insulin-induced hypoglycemia.
7- Fatigue (DUE TO reduce CO).

Question 16

• Drugs that lead to hypoglycemia are

Answer 16

insulin or oral sulfonylurea.

Question 17

How the B-blockers masking symptoms of hypoglycemia?

Answer 17

• Beta blocker will lead to hypoglycemia (decrease glucose level).
• Diabetes patient with hypoglycemia will feel this by sympathetic symptoms (tachycardia,
  tremor, sweating, palpitation), beta blocker will mask all hypoglycemia symptoms except
  sweating (because sweat glands have muscarinic receptor).

Question 18

cardioselective beta blocker is ?

Answer 18

Atenolol

Question 19

_______ used for Stable angina / diabetic hypertensive patients who are receiving insulin or oral antidiabetic agent

Answer 19

Atenolol

Question 20

Timolol is
selective/non ______ agonist/antagonist
used for

Answer 20

Nonselective, blocks B1and B2
local use in the eye because it lacks local anesthetic properties.
open-angle glaucoma.
- It reduces aqueous humor production through blockage of β receptors on the ciliary epithelium

Question 21

pilocarpine is similar to

Answer 21

Timolol

Question 22

Adverse effect of beta blocker:

Answer 22

Topical timolol may interact with orally administered verapamil and increase the risk of heart block.